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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi16 – 161Divalent metal cationUniRule annotation
Metal bindingi17 – 171Divalent metal cationUniRule annotation
Metal bindingi47 – 471Divalent metal cationUniRule annotation
Metal bindingi99 – 991Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1643-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:CBU_1671
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2582585'-nucleotidase SurEPRO_0000111807Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1671.

Structurei

Secondary structure

1
258
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi10 – 145Combined sources
Helixi22 – 3110Combined sources
Turni32 – 343Combined sources
Beta strandi35 – 4410Combined sources
Beta strandi59 – 635Combined sources
Beta strandi69 – 735Combined sources
Helixi75 – 828Combined sources
Turni83 – 864Combined sources
Beta strandi87 – 893Combined sources
Beta strandi92 – 10110Combined sources
Helixi105 – 1095Combined sources
Helixi112 – 1198Combined sources
Turni120 – 1234Combined sources
Beta strandi127 – 1326Combined sources
Beta strandi134 – 1363Combined sources
Helixi140 – 15617Combined sources
Beta strandi164 – 1696Combined sources
Helixi174 – 1763Combined sources
Beta strandi179 – 1824Combined sources
Beta strandi195 – 1984Combined sources
Beta strandi204 – 2074Combined sources
Beta strandi214 – 2163Combined sources
Helixi222 – 2276Combined sources
Beta strandi230 – 2367Combined sources
Helixi243 – 2453Combined sources
Helixi246 – 25611Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TY2X-ray1.88A/B1-258[»]
ProteinModelPortaliQ9KI21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9KI21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTATPKLR LLLSNDDGVY AKGLAILAKT LADLGEVDVV APDRNRSGAS
60 70 80 90 100
NSLTLNAPLH IKNLENGMIS VEGTPTDCVH LAITGVLPEM PDMVVAGINA
110 120 130 140 150
GPNLGDDVWY SGTVAAAMEG RFLGLPALAV SLGGELFRYY ETAAKVVYQL
160 170 180 190 200
IQRIEKDPLP PSTILNINVP DLPYEELKGF EVTRLGTRHR AEPTIRQIDP
210 220 230 240 250
RGHPIYWVGA AGPEQDSGPG TDFFAMNHHC VSITPLRVDL THYEAFDQLA

SWVKRLEM
Length:258
Mass (Da):28,066
Last modified:October 1, 2000 - v1
Checksum:iC620B037CBF471ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF244357 Genomic DNA. Translation: AAF73516.1.
AE016828 Genomic DNA. Translation: AAO91167.2.
RefSeqiNP_820653.2. NC_002971.3.
WP_005770587.1. NZ_CCNR01000011.1.

Genome annotation databases

EnsemblBacteriaiAAO91167; AAO91167; CBU_1671.
GeneIDi1209582.
KEGGicbu:CBU_1671.
PATRICi17932085. VBICoxBur82552_1661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF244357 Genomic DNA. Translation: AAF73516.1.
AE016828 Genomic DNA. Translation: AAO91167.2.
RefSeqiNP_820653.2. NC_002971.3.
WP_005770587.1. NZ_CCNR01000011.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TY2X-ray1.88A/B1-258[»]
ProteinModelPortaliQ9KI21.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227377.CBU_1671.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO91167; AAO91167; CBU_1671.
GeneIDi1209582.
KEGGicbu:CBU_1671.
PATRICi17932085. VBICoxBur82552_1661.

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1643-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSURE_COXBU
AccessioniPrimary (citable) accession number: Q9KI21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.