Reviewed, UniProtKB/Swiss-Prot Q9KHS2 (SSUD_PSESP)

Names and origin

Protein names

Recommended name:
    Alkanesulfonate monooxygenase
    EC=1.14.14.5
Alternative name(s):
    FMNH2-dependent aliphatic sulfonate monooxygenase

Gene names

Name:

ssuD

Organism

Pseudomonas sp.

Taxonomic identifier

306 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the desulfonation of aliphatic sulfonates By similarity. HAMAP MF_01229
Catalytic activity	An alkanesufonate (R-CH(2)-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O. HAMAP MF_01229
Sequence similarities	Belongs to the ssuD family.

Ontologies

Keywords
Ligand	FMN
Molecular function	Monooxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alkanesulfonate monooxygenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 382	382	Alkanesulfonate monooxygenase HAMAP MF_01229		PRO_0000216715
Natural variations
	Natural variant	31	1	Y → H in strain: PSBZ.
	Natural variant	70 – 71	2	ER → QH in strain: Blue1.
	Natural variant	105 – 106	2	FN → IP in strain: PSBZ.
	Natural variant	167	1	V → I in strain: Blue1.
	Natural variant	253	1	D → E in strain: Blue1.
	Natural variant	347	1	L → P in strain: PSBZ and Blue1.
	Natural variant	349	1	I → L in strain: Blue1.

Sequences

	Sequence		Length	Mass (Da)
	Q9KHS2-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 59BEAF5B0059D770	FASTA	382	41,496
	10 20 30 40 50 60 MSLNIFWFLP THGDGKYLGT SDGARAVDHG YLQQIAQAAD RLGFGGVLIP TGRSCEDSWL 70 80 90 100 110 120 VAASLIPVTE RLKFLVALRP GIISPTVAAR QAATLDRLSN GRALFNLVTG GDPDELAGDG 130 140 150 160 170 180 LHLNHQERYE ASVEFTRIWR KVLEGENVDY DGKHIQVKGA KLLYPPVQQP RPPLYFGGSS 190 200 210 220 230 240 EAAQDLAAEQ VELYLTWGEP PAAVAEKIAQ VREKAAAQGR EVRFGIRLHV IVRETNEEAW 250 260 270 280 290 300 AAADRLISHL DDDTIARAQA SLARFDSVGQ QRMAALHGGN RDNLEVSPNL WAGVGLVRGG 310 320 330 340 350 360 AGTALVGDGP TVAARVKEYA DLGIDTFIFS GYPHLEESYR VAELLFLHID VQRPEQPKTG 370 380 GYVSPFGEMV ANDILPKSVS QS

References

[1]

"Sulfur-controlled aryl desulfonation phenotypes in Pseudomonas spp. and other soil isolates, and conservation of the sulfonate monooxygenase gene (ssuD)." Kertesz M.A., Sialm M. Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Blue1, PSBZ and Tar2A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF250866 Genomic DNA. Translation: AAF81701.1. AF250867 Genomic DNA. Translation: AAF81704.1. AF250868 Genomic DNA. Translation: AAF81707.1.
3D structure databases
SMR	Q9KHS2. Positions 1-358.
ModBase	Search...
Family and domain databases
HAMAP	MF_01229. Alkanesulf_monooxygen. [Tree]
InterPro	IPR019911. Alkanesulphonate_mOase_FMN-dep. IPR011251. Luciferase-like. [Graphical view]
Gene3D	G3DSA:3.20.20.30. Luciferase_like. 1 hit.
TIGRFAMs	TIGR03565. Alk_sulf_monoox. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SSUD_PSESP

Accession

Primary (citable) accession number: Q9KHS2
Secondary accession number(s): Q9KHR6, Q9KHR9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2003
Last sequence update:	October 1, 2000
Last modified:	February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)