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Protein

Uronate isomerase

Gene

uxaC

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathway:ipentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciNPUN63737:GJNP-5205-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Synonyms:hrmI
Ordered Locus Names:Npun_F5333
OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)
Taxonomic identifieri63737 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
ProteomesiUP000001191 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 472472Uronate isomerasePRO_0000172777Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi63737.Npun_F5333.

Structurei

3D structure databases

ProteinModelPortaliQ9KHA1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1904.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9KHA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTKKPVLSP DRCFSPEPVQ RRLAHQFFDS ISALPLVCPH GHVDPALLAN
60 70 80 90 100
PAARFGSPTE LFIIPDHYIL RMLYSRGVPL EALGIPTRDA PTETDHRKIW
110 120 130 140 150
QLFAEHFYLF QGTPSGLWLK DELTNVFGVD EALNSRNAGR IYDYLEGLLA
160 170 180 190 200
LPKFSPRALF KRFNIEVLCT TDAASDNLEN QRSLHEEGFT QIRPTFRPDA
210 220 230 240 250
VVNLDAPGWR ENLTKLESSI GREISSYATF VQALEERRAF FKKMGATATD
260 270 280 290 300
QGAATPYTTS LSDQEAEAIF ARALIGKLNP GDVEQFTGHI FMEMARMSVE
310 320 330 340 350
DGLVMQMHCG VMRNHNPALF ERFGSDKGAD IPLNIEWTRN LHPLLSSYGN
360 370 380 390 400
NQRFRLIIFG MDESTYSREM APLAGHYPTI LLGPPWWFHD SVNGMERYFN
410 420 430 440 450
QVMETAGIYN TAGFNDDTRA FVSIPARHNV WRRVACNWLA GLVTRGLVDE
460 470
EEGYDMARAL AYDLAKSAYK LD
Length:472
Mass (Da):53,319
Last modified:October 1, 2000 - v1
Checksum:i77770A09BE169BFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF266466 Genomic DNA. Translation: AAF77061.1.
CP001037 Genomic DNA. Translation: ACC83652.1.
RefSeqiWP_012411603.1. NC_010628.1.

Genome annotation databases

EnsemblBacteriaiACC83652; ACC83652; Npun_F5333.
KEGGinpu:Npun_F5333.
PATRICi22764166. VBINosPun48114_6218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF266466 Genomic DNA. Translation: AAF77061.1.
CP001037 Genomic DNA. Translation: ACC83652.1.
RefSeqiWP_012411603.1. NC_010628.1.

3D structure databases

ProteinModelPortaliQ9KHA1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi63737.Npun_F5333.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC83652; ACC83652; Npun_F5333.
KEGGinpu:Npun_F5333.
PATRICi22764166. VBINosPun48114_6218.

Phylogenomic databases

eggNOGiCOG1904.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciNPUN63737:GJNP-5205-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Campbell E.L., Meeks J.C., Wong F.C.
    Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29133 / PCC 73102.

Entry informationi

Entry nameiUXAC_NOSP7
AccessioniPrimary (citable) accession number: Q9KHA1
Secondary accession number(s): B2J4G2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: October 1, 2000
Last modified: July 22, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.