Q9KGJ3 (PTH_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29

Gene names

Name:	pth
Synonyms:	spoVC
Ordered Locus Names:	BH0068

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083
Subunit structure	Monomer By similarity. HAMAP MF_00083
Subcellular location	Cytoplasm By similarity HAMAP MF_00083.
Sequence similarities	Belongs to the PTH family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Peptidyl-tRNA hydrolase HAMAP MF_00083		PRO_0000187688

Sequences

	Sequence		Length	Mass (Da)
	Q9KGJ3 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: AAC87F8B5354269D	FASTA	185	20,548
	10 20 30 40 50 60 MKLIVGLGNP GAKYDGTRHN VGFDVVDAVA RRLNIEIKQS KANGLYGEGR IDGEKIFLLK 70 80 90 100 110 120 PQTFMNRSGE SVRPFLEYYN MEVEDLLVIY DDLDLPVGKI RLRQKGSAGG HNGMKSLIAH 130 140 150 160 170 180 LGTSDFKRIR VGVDRPAPGE TVVQHVLGRY RPEEKDAISE AIDLSAEAAE AFTKKPFLEV MNTFN

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB03787.1.
PIR	D83658.
RefSeq	NP_240934.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9KGJ3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050621; EBBACP00000049260; EBBACG00000050612.
GeneID	892331.
GenomeReviews	Gene locus BH0068 in contig BA000004_GR.
KEGG	bha:BH0068.
NMPDR	fig|272558.1.peg.68.
PATRIC	18936966. VBIBacHal18977_0073.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000001189.
HOGENOM	HBG610927.
OMA	NTFMNNS.
PhylomeDB	Q9KGJ3.
ProtClustDB	PRK05426.
Enzyme and pathway databases
BioCyc	BHAL272558:BH0068-MONOMER.
Family and domain databases
HAMAP	MF_00083. Pept_tRNA_hydro_bact. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KO	K01056.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. Pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTH_BACHD

Accession

Primary (citable) accession number: Q9KGJ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program