Q9KG96 (Q9KG96_BACHD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Dihydrolipoyl dehydrogenase RuleBase RU003692
EC=1.8.1.4 RuleBase RU003692

Gene names

Ordered Locus Names:

BH0216

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	473 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH. RuleBase RU003692
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003692
Miscellaneous	The active site is a redox-active disulfide bond By similarity. RuleBase RU003692
Sequence similarities	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003691

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003691
Ligand	FAD RuleBase RU003691 Flavoprotein RuleBase RU003691 NAD RuleBase RU003692 Pyruvate EMBL BAB03935.1
Molecular function	Oxidoreductase RuleBase RU003691 EMBL BAB03935.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	dihydrolipoyl dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9KG96 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 07FE5600439FA489	FASTA	473	50,044
	10 20 30 40 50 60 MVVGEVAVEV DTVVVGGGPG GYTAAIRLGQ LGKSVVLIEK NQLGGVCLNR GCIPSKALIQ 70 80 90 100 110 120 MAEKFDELTH LKEMGVELPG KPASIDLHKW QKWKQEITTK LNTGIHQLCQ QNGVTVVTGE 130 140 150 160 170 180 AHFLSSHRVG VETGNAFDVY KFEHAIVATG SSPRSLPFAE VDHTYILDST SALELTEVPR 190 200 210 220 230 240 SLSIVGGGYI GMELGLAFAK LGSAVTIVEM SPHILPATAP HISREVLNKA EKLGVTIKSS 250 260 270 280 290 300 TSVEHLTVND GYVELIVQSN GEQETLQSEK ALMTVGRSPN TKGLGLEQVG VFFNEDGTLP 310 320 330 340 350 360 INEECRTNID HIFAIGDVTE GPALAHKASK QGIVAAEVIG GLPSAIDSSY IPYVVFTDPQ 370 380 390 400 410 420 IAGVGLTAKQ AQEQGHRVKT ARFPFQANGL ALVASKPDGF AEVIVDEESH LLLGFHIVGA 430 440 450 460 470 DASNLIGEGV LALELGARVE DVALTVHPHP TFSEGWLGAA EAALGHAIHV VNK

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB03935.1.
PIR	H83676.
RefSeq	NP_241082.1. NC_002570.2.
3D structure databases
HSSP	HSSP built from PDB template 1EBD based on UniProtKB P11959.
ProteinModelPortal	Q9KG96.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000054025; EBBACP00000052664; EBBACG00000054016.
GeneID	893539.
GenomeReviews	Gene locus BH0216 in contig BA000004_GR.
KEGG	bha:BH0216.
NMPDR	fig|272558.1.peg.216.
PATRIC	18937306. VBIBacHal18977_0225.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00070000031801.
HOGENOM	HBG515043.
OMA	IVDEESH.
PhylomeDB	Q9KG96.
ProtClustDB	CLSK2459865.
Family and domain databases
InterPro	IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR006258. Lipoamide_DH. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR012999. Pyr_OxRdtase_I_AS. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view]
Gene3D	G3DSA:3.30.390.30. Pyr_redox_dim. 1 hit.
KO	K00382.
PANTHER	PTHR22912:SF20. Lipoamide_DH. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. PF02852. Pyr_redox_dim. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
TIGRFAMs	TIGR01350. Lipoamide_DH. 1 hit.
PROSITE	PS00076. PYRIDINE_REDOX_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9KG96_BACHD

Accession

Primary (citable) accession number: Q9KG96

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)