Q9KG60 (URE2_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit beta
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit beta

Gene names

Name:	ureB
Ordered Locus Names:	BH0253

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	124 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP MF_01954
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_01954
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01954.
Sequence similarities	Belongs to the urease beta subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 124	124	Urease subunit beta HAMAP MF_01954		PRO_0000234227

Sequences

	Sequence		Length	Mass (Da)
	Q9KG60 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: E33D948F7DA7CBB3	FASTA	124	13,792
	10 20 30 40 50 60 MIPGEVIPAN GEVVLNKGRR MVKVLVAHTG DRPIQVGSHF HFAEVNRSLH FDRQEAFGMR 70 80 90 100 110 120 LNIAAGTAVR FEPGEEKEVD LVEIGGKRQI YGLNGWTDGA IDDENLPSFL ASYQVSEDKE DEEK

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB03972.1.
PIR	E83681.
RefSeq	NP_241119.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9KG60.
SMR	Q9KG60. Positions 1-101.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000052008; EBBACP00000050647; EBBACG00000051999.
GeneID	893531.
GenomeReviews	Gene locus BH0253 in contig BA000004_GR.
KEGG	bha:BH0253.
NMPDR	fig|272558.1.peg.253.
PATRIC	18937400. VBIBacHal18977_0267.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002380.
HOGENOM	HBG365918.
OMA	PLSGKRE.
Enzyme and pathway databases
BioCyc	BHAL272558:BH0253-MONOMER.
Family and domain databases
HAMAP	MF_01954. Urease_beta. [Tree]
InterPro	IPR002019. Urease_beta. [Graphical view]
Gene3D	G3DSA:2.10.150.10. Urease_beta. 1 hit.
KO	K01429.
Pfam	PF00699. Urease_beta. 1 hit. [Graphical view]
SUPFAM	SSF51278. Urease_beta. 1 hit.
TIGRFAMs	TIGR00192. Urease_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE2_BACHD

Accession

Primary (citable) accession number: Q9KG60

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2006
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program