Q9KG46 (GLMM_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BH0267

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147844
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KG46 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: AA9E7158685D4023	FASTA	447	48,120
	10 20 30 40 50 60 MGKYFGTDGV RGVANTELTP ELAFKLGRIG GYVLTKDKEN PKVLIGRDTR ISGEMLEGAL 70 80 90 100 110 120 VAGLLSIGVE VMRLGVISTP GVAFLTKAVS ASAGVMISAS HNPVADNGIK FFGPDGFKLL 130 140 150 160 170 180 DEQEKEIETL LDQEDALPRP TGADLGQAND YFEGAQKYLQ FLKQTVDEDF TGIHIALDCA 190 200 210 220 230 240 NGAASSLAPH LFADLEADIS TMGTSPNGKN INDGVGSTHP EALAAFVNAK NADIGLAFDG 250 260 270 280 290 300 DADRLIAVDE KGNIVDGDKI LYICAKYMKE KGLLKQQTLV TTVMSNLGLY KALEALQIDT 310 320 330 340 350 360 KQTAVGDRYV MEEMRKGGYN LGGEQSGHII FLDHITTGDG MLSALQLVNI MKQTGKKLSE 370 380 390 400 410 420 LAEEWETFPQ TLVNIRVTDK HAVTDNEKVP AVIKEVEQEM NGEGRVLVRP SGTEPLVRIM 430 440 VEAKTEELCD AFVNKIADVV KAELGQE

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB03986.1.
PIR	C83683.
RefSeq	NP_241133.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9KG46.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050406; EBBACP00000049045; EBBACG00000050397.
GeneID	894435.
GenomeReviews	Gene locus BH0267 in contig BA000004_GR.
KEGG	bha:BH0267.
NMPDR	fig|272558.1.peg.267.
PATRIC	18937446. VBIBacHal18977_0282.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00070000032132.
HOGENOM	HBG644964.
OMA	GVGSTHL.
PhylomeDB	Q9KG46.
ProtClustDB	CLSK2748835.
Enzyme and pathway databases
BioCyc	BHAL272558:BH0267-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BACHD

Accession

Primary (citable) accession number: Q9KG46

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program