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Q9KFI7 (UXAB_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Altronate oxidoreductase

EC=1.1.1.58
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene names
Name:uxaB
Ordered Locus Names:BH0492
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP-Rule MF_00670

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00670

Sequence similarities

Belongs to the mannitol dehydrogenase family. UxaB subfamily.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

tagaturonate reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 512512Altronate oxidoreductase HAMAP-Rule MF_00670
PRO_0000170738

Regions

Nucleotide binding26 – 3712NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9KFI7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D27D7862C2913A05

FASTA51258,450
        10         20         30         40         50         60 
MEKLSHGLVT SRNMIRYKSS QLPERVLQFG EGNFLRGFID WMIQQMNKQN VFNGRVVAIQ 

        70         80         90        100        110        120 
PTPHGKVVPK LQEQDSLYTV WLRGIADGET VDHHEVITSI SRGLNPYTNW QDVLEVAASP 

       130        140        150        160        170        180 
DISVVFSNTT EAGLTYLEEG YDKEKAPLSF PGKLAACLWH RYETLGWGEG SGLVIIPCEL 

       190        200        210        220        230        240 
VEQNGKVLKE LVCRYAKAWN FPQEFFTWLE RENEFCHTLV DRIVPGFPSD TADECFERLG 

       250        260        270        280        290        300 
YEDILLTVAE PYHLFIIEGS ERVRKLLPFN EAGLHVRWNH LEKHRNMKVR VLNGTHTFMF 

       310        320        330        340        350        360 
ALSYLSGVDT VGEAMADEQL CSFIRKGLFE EIIPCVDAPE QEVTAFAETV LERFENPFLQ 

       370        380        390        400        410        420 
HRLTDIGLNA VNKFRTRLMP TFNDYVAQTG EAPTYLLFSL AALINYYRGV EEDGPFLIGR 

       430        440        450        460        470        480 
RREDSYLIRD DLEVIEAFKV GWQQVNTGKL SLAQLCEDLL SKRELWGVDL SMERKVVDKV 

       490        500        510 
AESLQIIVEK GMRQAISGVL NQIGGNNHVH KQ 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB04211.1.
PIRD83711.
RefSeqNP_241358.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9KFI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH0492.

Protocols and materials databases

DNASU892054.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB04211; BAB04211; BAB04211.
GeneID892054.
KEGGbha:BH0492.
PATRIC18937920. VBIBacHal18977_0519.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
KOK00041.
OMARFNNPFV.
OrthoDBEOG6CVVB8.
ProtClustDBPRK03643.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-529-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00670. Altron_oxidoreduct.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMSSF48179. SSF48179. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXAB_BACHD
AccessionPrimary (citable) accession number: Q9KFI7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways