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Q9KFH8 (Q9KFH8_BACHD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Name:nrdA EMBL BAB04220.1
Ordered Locus Names:BH0501
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length726 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Sequences

Sequence LengthMass (Da)Tools
Q9KFH8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: A2E2A90063C55352

FASTA72683,351
        10         20         30         40         50         60 
MTMTINKELH WQERLKERFP QLEVEDVLSQ GASLESMRMK AMDEISAEQP EWTFITARIY 

        70         80         90        100        110        120 
LEELYNSVKE QRGLAKPYTQ FYELIEVLVD KGIYEKDLLN RYTKEEINEL GEHLNQEKDE 

       130        140        150        160        170        180 
LFTYIGLKTL ADRYLARLYD RTLMELPQER FMVIAMSLMK KEVNSQRLSL VKEAYWALSN 

       190        200        210        220        230        240 
LYMTVATPTF ANAGKAVGQL SSCFIDTVDD SLRGIFDSCT DAATVSKSGG GLGIYLGKIR 

       250        260        270        280        290        300 
AKGSSIKNYQ NVSSGVLPWM KQLNNVAVSV DQLGQRQGAI AVYLDIWHKD IFSFLDAKLN 

       310        320        330        340        350        360 
NGDERQRTHD LFTAVSLPDL FMEAVEARDN WYLFDPHEIR QKMGFSLEDS YDEQKGSGTF 

       370        380        390        400        410        420 
RERYEACVNN PDLSRTEVPA IEIMKRIMIS QLETGSPFMY YRDEANRMNP NKHEGMVYGS 

       430        440        450        460        470        480 
NLCTEIIQNM SPTTVVEEKT EDGKILITKQ PGDYVVCNLS SLSLARVVED DVLERLIPIQ 

       490        500        510        520        530        540 
VRMLDNVIDV NRIEVKQAEQ TNQKYRAIGL GTYGWHHLLA KKGIAWESEE AIRYADELYE 

       550        560        570        580        590        600 
TINYLTIQAS MKLAEEKGAY PMFGGSDWET GEYFERRQYT TDKWTELAEQ VKEKGLRNGY 

       610        620        630        640        650        660 
LLAVAPNATT ALIGGTTASI DPIFQKTYVE EKKNYRIPVT APDLSPETTW YYKSAYHIDQ 

       670        680        690        700        710        720 
TWSIRQNGAR QRHVDQSISF NLYVSNTIRA KELLELHLLA WKEGLKTTYY LRSTSMEIED 


CESCAS

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References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000004 Genomic DNA. Translation: BAB04220.1.
PIRE83712.
RefSeqNP_241367.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9KFH8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000051657; EBBACP00000050296; EBBACG00000051648.
GeneID893381.
GenomeReviewsGene locus BH0501 in contig BA000004_GR.
KEGGbha:BH0501.
NMPDRfig|272558.1.peg.501.
PATRIC18937942. VBIBacHal18977_0530.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000001799.
HOGENOMHBG296647.
OMARHVDQSI.
PhylomeDBQ9KFH8.
ProtClustDBPRK09209.

Family and domain databases

InterProIPR013346. NrdE_NrdA.
IPR013509. Ribncl_Rdtase_lsu_N.
IPR000788. Ribncl_red_lg_C.
IPR008926. Ribnucl_Rdtase_R1-su_N.
[Graphical view]
KOK00525.
PfamPF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
TIGRFAMsTIGR02506. NrdE_NrdA. 1 hit.
PROSITEPS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9KFH8_BACHD
AccessionPrimary (citable) accession number: Q9KFH8
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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