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Q9KF76 (Q9KF76_BACHD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Sulfite reductase (NADPH) EMBL BAB04328.1
Gene names
Ordered Locus Names:BH0609
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length607 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component By similarity. SAAS SAAS003097

Catalytic activity

H2S + 3 NADP+ + 3 H2O = sulfite + 3 NADPH. SAAS SAAS003097

Cofactor

Binds 1 FAD per subunit By similarity. SAAS SAAS003097

Binds 1 FMN per subunit By similarity. SAAS SAAS003097

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1. SAAS SAAS003097

Subunit structure

Alpha(8)-beta8. The alpha component is a flavoprotein, the beta component is a hemoprotein By similarity. SAAS SAAS003097

Sequence similarities

Contains 1 FAD-binding FR-type domain. SAAS SAAS010199

Contains 1 flavodoxin-like domain. SAAS SAAS010199

Sequences

Sequence LengthMass (Da)Tools
Q9KF76 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 3CD1B0EAA1DBFFBE

FASTA60767,866
        10         20         30         40         50         60 
MQLQVMNSPF NEEQVELLNR LLPTLNASQK AWLSGYLTAI QSADTATVLE AVPAAAPAAN 

        70         80         90        100        110        120 
TAQPVSKEVT ILFGSQTGNA QGLAENAGKT LKEQGFQVTV SSMSDFKPNQ LKKLKNLLIV 

       130        140        150        160        170        180 
VSTHGEGDPP DNALSFHEFL HGRRAPKLED LRYSVLALGD TSYEFFCKTG KDFDQRLEAL 

       190        200        210        220        230        240 
GATRLQPCVE CDLDFEEPAA KWLEGVITRL SEGQGQTVPA QPTAPEAKAV ETVYSRKNPF 

       250        260        270        280        290        300 
RAEVLENINL NGRGSNKETR HLELSLEGSG LTYEPGDALG IFPENDPELV DLLLNELKWD 

       310        320        330        340        350        360 
ANEVVAVDKQ GERLPLKEAL TSYFEITVLT KKLIQQAAEL LDNEKLRALT ASENAQQLKA 

       370        380        390        400        410        420 
YIDGRDLVDF VRDFGPINAS PQEFVSILRK MPPRLYSIAS SIAANPEEVH LTIGAVRYHA 

       430        440        450        460        470        480 
HGRDRKGVCS ILCAERLQPG DTVPMFIQPN KNFKLPESPE TPIIMVGPGT GVAPFRSFMQ 

       490        500        510        520        530        540 
EREEAGATGK SWMFFGDQHF VTDFLYQTEW QKWLKDGVLT RMDVAFSRDT EEKVYVQHRM 

       550        560        570        580        590        600 
LEHSKELYKW LEEGAVFYVC GDKTNMAKDV QEALLEIIEK EGGKSREEAE AYLAEMKKQK 


RYQRDVY

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References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000004 Genomic DNA. Translation: BAB04328.1.
PIRA83726.
RefSeqNP_241475.1. NC_002570.2.

3D structure databases

HSSPHSSP built from PDB template 1DDG based on UniProtKB P38038.
ProteinModelPortalQ9KF76.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000050994; EBBACP00000049633; EBBACG00000050985.
GeneID893171.
GenomeReviewsGene locus BH0609 in contig BA000004_GR.
KEGGbha:BH0609.
NMPDRfig|272558.1.peg.609.
PATRIC18938194. VBIBacHal18977_0640.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000001044.
HOGENOMHBG736048.
OMAESADEYL.
PhylomeDBQ9KF76.
ProtClustDBCLSK2748874.

Family and domain databases

InterProIPR010199. CysJ.
IPR003097. FAD-binding_1.
IPR017927. Fd_Rdtase_FAD-bd.
IPR001094. Flavdoxin.
IPR008254. Flavodoxin/NO_synth.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR023173. NADPH_Cyt_P450_Rdtase_dom3.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
Gene3DG3DSA:1.20.990.10. NADPH_Cyt_P450_Rdtase_dom3. 1 hit.
KOK00380.
PfamPF00667. FAD_binding_1. 1 hit.
PF00258. Flavodoxin_1. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PIRSFPIRSF000207. SiR-FP_CysJ. 1 hit.
PRINTSPR00369. FLAVODOXIN.
PR00371. FPNCR.
SUPFAMSSF63380. Riboflavin_synthase_like_b-brl. 1 hit.
TIGRFAMsTIGR01931. CysJ. 1 hit.
PROSITEPS51384. FAD_FR. 1 hit.
PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9KF76_BACHD
AccessionPrimary (citable) accession number: Q9KF76
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info