Reviewed, UniProtKB/Swiss-Prot Q9KEZ3 (UXUA2_BACHD)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase 2
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase 2

Gene names

Name:	uxuA2
Ordered Locus Names:	BH0706

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	Mannonate dehydratase 2 HAMAP MF_00106		PRO_0000170661

Sequences

	Sequence		Length	Mass (Da)
	Q9KEZ3-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: E219AA943820EBEA	FASTA	345	38,888
	10 20 30 40 50 60 MRLTMRWFGP SDKVKLEYIK QIPGMKGIVS AIYDVAVGGV WPKEKILALK NNIERHGLTL 70 80 90 100 110 120 DVIESVPVHE DIKLGKPTRD RYIENYKQTL RHLAECGIDT VCYNFMPVFD WTRSQLDFKL 130 140 150 160 170 180 EDGSEALIYE EDVISRTNPL SGELELPGWD TSYENESLKG VLQAYKKISE EDLWDHLTYF 190 200 210 220 230 240 VQAIMPVADE VGIKMAIHPD DPPWSIFGLP RIVTNKANLE RLLSLYDSPN HGITMCSGSL 250 260 270 280 290 300 GANEANDLPE MIRHFGGQGR IHFAHARNIK RTGPRSFQES AHLSEAGSVN MVAMLKAYHD 310 320 330 340 IGFTGPLRPD HGRMIWGEKG RPGYGLYDRA LGATYLNGIW EAVSS

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB04425.1.
PIR	B83738.
RefSeq	NP_241572.1.
3D structure databases
SMR	Q9KEZ3. Positions 1-345.
ModBase	Search...
Genome annotation databases
GeneID	892990.
GenomeReviews	Gene locus BH0706 in contig BA000004_GR.
KEGG	bha:BH0706.
NMPDR	fig|272558.1.peg.706.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG585927.
OMA	DIKLGKP.
PhylomeDB	Q9KEZ3.
Enzyme and pathway databases
BioCyc	BHAL272558:BH0706-MONOMER.
BRENDA	4.2.1.8. 191865.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA2_BACHD

Accession

Primary (citable) accession number: Q9KEZ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2002
Last sequence update:	October 1, 2000
Last modified:	February 9, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)