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Protein

Arginine--tRNA ligase 2

Gene

argS2

Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase 2 (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase 2
Short name:
ArgRS 2
Gene namesi
Name:argS2
Ordered Locus Names:BH0834
OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Taxonomic identifieri272558 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001258 Componenti: Chromosome

Subcellular locationi

Q9KEL8:

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515291 – 561Arginine--tRNA ligase 2Add BLAST561

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi272558.BH0834.

Structurei

3D structure databases

ProteinModelPortaliQ9KEL8.
SMRiQ9KEL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi117 – 127"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9KEL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAQMISEEL ARILSLKEDE VERLLEIPPQ ETLGDLAFPC FTLAKTKRKA
60 70 80 90 100
PPFIAAELEA AFLEHKEVTA KATGGYVNFF FHRETVAGQL FQEMKSNQYW
110 120 130 140 150
QPNSGDGKRV VIDMSSPNIA KPFGIGHLRS TIIGHALYHL LKKTGYDPIR
160 170 180 190 200
VNHLGDWGTQ FGKQIAAYQR WGGDVDLKQN PIASFLELYV RFHEEAEKDE
210 220 230 240 250
SLEDEGREWF KKLEEGDEEA DRLWTYFVKE SLNEFDRMYN RLGVEFDYVL
260 270 280 290 300
GESFYNDQMA PVVKELQEKG LLTCSEGALV VPLEDADLPP CLIVKSDGTS
310 320 330 340 350
IYATRDLATA IYRHHVQKGE KLLYVVGGEQ TLHFKQVFHV LKKMGYKWAD
360 370 380 390 400
QCEHITFGLL RLDGKKMSTR RGRVVMLEDV LNDVVAHAKA KIKEKHPNHP
410 420 430 440 450
HLHEVAEAVG VGAVIFGDLK QDRRLDVNFR LEDALSFEGE TGPYVQYTYA
460 470 480 490 500
RIQSILRKGD KLNDSRHMDW QHVTKDEGWS LLKVLIQYPN VLIKATEARE
510 520 530 540 550
PHQLARYVLT VSKKFNQFYH KYVILADDET VRQARLILAE RTGEVIADAM
560
AVLGVKTPEE L
Length:561
Mass (Da):64,133
Last modified:October 1, 2000 - v1
Checksum:iC9C544BF1DE1A1FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000004 Genomic DNA. Translation: BAB04553.1.
PIRiB83754.
RefSeqiWP_010897007.1. NC_002570.2.

Genome annotation databases

EnsemblBacteriaiBAB04553; BAB04553; BAB04553.
KEGGibha:BH0834.

Similar proteinsi

Entry informationi

Entry nameiSYR2_BACHD
AccessioniPrimary (citable) accession number: Q9KEL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: October 1, 2000
Last modified: October 25, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families