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Q9KEL8 (SYR2_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase 2

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase 2
Short name=ArgRS 2
Gene names
Name:argS2
Ordered Locus Names:BH0834
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Arginine--tRNA ligase 2 HAMAP-Rule MF_00123
PRO_0000151529

Regions

Motif117 – 12711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q9KEL8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: C9C544BF1DE1A1FF

FASTA56164,133
        10         20         30         40         50         60 
MLAQMISEEL ARILSLKEDE VERLLEIPPQ ETLGDLAFPC FTLAKTKRKA PPFIAAELEA 

        70         80         90        100        110        120 
AFLEHKEVTA KATGGYVNFF FHRETVAGQL FQEMKSNQYW QPNSGDGKRV VIDMSSPNIA 

       130        140        150        160        170        180 
KPFGIGHLRS TIIGHALYHL LKKTGYDPIR VNHLGDWGTQ FGKQIAAYQR WGGDVDLKQN 

       190        200        210        220        230        240 
PIASFLELYV RFHEEAEKDE SLEDEGREWF KKLEEGDEEA DRLWTYFVKE SLNEFDRMYN 

       250        260        270        280        290        300 
RLGVEFDYVL GESFYNDQMA PVVKELQEKG LLTCSEGALV VPLEDADLPP CLIVKSDGTS 

       310        320        330        340        350        360 
IYATRDLATA IYRHHVQKGE KLLYVVGGEQ TLHFKQVFHV LKKMGYKWAD QCEHITFGLL 

       370        380        390        400        410        420 
RLDGKKMSTR RGRVVMLEDV LNDVVAHAKA KIKEKHPNHP HLHEVAEAVG VGAVIFGDLK 

       430        440        450        460        470        480 
QDRRLDVNFR LEDALSFEGE TGPYVQYTYA RIQSILRKGD KLNDSRHMDW QHVTKDEGWS 

       490        500        510        520        530        540 
LLKVLIQYPN VLIKATEARE PHQLARYVLT VSKKFNQFYH KYVILADDET VRQARLILAE 

       550        560 
RTGEVIADAM AVLGVKTPEE L 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB04553.1.
PIRB83754.
RefSeqNP_241700.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9KEL8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH0834.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB04553; BAB04553; BAB04553.
GeneID892340.
KEGGbha:BH0834.
PATRIC18938676. VBIBacHal18977_0876.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAKPFGIGH.
OrthoDBEOG6JB13C.
ProtClustDBPRK12451.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-892-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR2_BACHD
AccessionPrimary (citable) accession number: Q9KEL8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries