Reviewed, UniProtKB/Swiss-Prot Q9KDZ8 (UXUA1_BACHD)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase 1
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase 1

Gene names

Name:	uxuA1
Ordered Locus Names:	BH1063

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	361 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 361	361	Mannonate dehydratase 1 HAMAP MF_00106		PRO_0000170660

Sequences

	Sequence		Length	Mass (Da)
	Q9KDZ8-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 4C45A43278E1E732	FASTA	361	41,633
	10 20 30 40 50 60 MRMVFRWFGA GNDSVSLAHI RQIPGVEGIV WALHDIPPGE VWPLSRIMEI KEQAEQHQFH 70 80 90 100 110 120 IDVVESVNVH EDIKLGLPTR DRYIEAYKQT IKHLAKAGVK VICYNFMPVF DWVRTDLYKK 130 140 150 160 170 180 LEDGSTALFY EKKEVDEMNP KGLVETIASN KTFTMPGWEP ERLASLKTLF EAYEHVSTED 190 200 210 220 230 240 LWDHLHYFLQ EVIPVAEACD IKMAIHPDDP PWPIFGLPRI VTNHDNIRRL LKLVDHPTNG 250 260 270 280 290 300 ITLCSGALGA DPNNQVPEMI REFADRIPFA HIRNIKRFDN GDFVETSHRE QDGSIDIVSI 310 320 330 340 350 360 VKAYHEVGFT GYVRPDHGRH IWDEQCRPGY GLYDRALGIM YLWGIWDSVQ NGQRMHDLTA K

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000004 Genomic DNA. Translation: BAB04782.1.
PIR	G83782.
RefSeq	NP_241929.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	892310.
GenomeReviews	Gene locus BH1063 in contig BA000004_GR.
KEGG	bha:BH1063.
NMPDR	fig|272558.1.peg.1063.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9KDZ8.
OMA	ALGIMYL.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1063-MON.
BRENDA	4.2.1.8. 191865.
Family and domain databases
HAMAP	MF_00106. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA1_BACHD

Accession

Primary (citable) accession number: Q9KDZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)