Reviewed, UniProtKB/Swiss-Prot Q9KDQ1 (NTPA1_BACHD)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase 1
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase 1
      Short name=NTPase 1

Gene names

Ordered Locus Names:

BH1160

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Nucleoside-triphosphatase 1 HAMAP MF_01405		PRO_0000178124

Sequences

	Sequence		Length	Mass (Da)
	Q9KDQ1-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: D41FAE0F2E0AB97D	FASTA	193	21,792
	10 20 30 40 50 60 MHKLVIATWN KEKRDELSRY FQQMDVSIQS LRGDIPDVKE TGATFIENAR LKAEAVRQYE 70 80 90 100 110 120 PTAIIVAEDS GLCVDALDGF PNVRTARFME GTDDERAAKV LQRLGDRPMS ERTAVFQSAV 130 140 150 160 170 180 VILFPDGLMR TAVGKIEGWI TYGPVKDGQG YGGIFILCDE QLLAENIQMA RCNHRSQAIR 190 QAVYYMEEWL VTV

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000004 Genomic DNA. Translation: BAB04879.1.
PIR	H83794.
RefSeq	NP_242026.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	894137.
GenomeReviews	Gene locus BH1160 in contig BA000004_GR.
KEGG	bha:BH1160.
NMPDR	fig|272558.1.peg.1160.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9KDQ1.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1160-MON.
BRENDA	3.6.1.15. 191865.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTPA1_BACHD

Accession

Primary (citable) accession number: Q9KDQ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2002
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)