Reviewed, UniProtKB/Swiss-Prot Q9KD67 (DEOC_BACHD)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Synonyms:	dra
Ordered Locus Names:	BH1352

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 224	224	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000057223
Sites
	Active site	155	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	184	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KD67-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 5CC79183BB424502	FASTA	224	23,362
	10 20 30 40 50 60 MSRSIAQMID HTLLKPNTTE DQIVKLCEEA KEYSFASVCV NPTWVALAAQ LLKDAPDVKV 70 80 90 100 110 120 CTVIGFPLGA TTPEVKAFET TNAIENGATE VDMVINIGAL KDKQYELVGR DIQAVVKAAE 130 140 150 160 170 180 GKALTKVIIE TSLLTEEEKK AACELAVKAG ADFVKTSTGF SGGGATAEDI ALMRKVVGPN 190 200 210 220 LGVKASGGVR DLSDAKAMID AGATRIGASA GVAIVNGERS EGSY

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB05071.1.
PIR	H83818.
RefSeq	NP_242218.1.
3D structure databases
SMR	Q9KD67. Positions 3-221.
ModBase	Search...
Genome annotation databases
GeneID	892275.
GenomeReviews	Gene locus BH1352 in contig BA000004_GR.
KEGG	bha:BH1352.
NMPDR	fig|272558.1.peg.1352.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG636421.
OMA	AKMIDHT.
PhylomeDB	Q9KD67.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1352-MONOMER.
BRENDA	4.1.2.4. 191865.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_BACHD

Accession

Primary (citable) accession number: Q9KD67

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	October 1, 2000
Last modified:	February 9, 2010
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)