Q9KD49 (SYGA_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycyl-tRNA synthetase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycine--tRNA ligase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	BH1370

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 297	297	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_0000072826

Sequences

	Sequence		Length	Mass (Da)
	Q9KD49-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: F277D6C2C74969E7	FASTA	297	34,421
	10 20 30 40 50 60 MNVQTMILTL QEYWSKQNCI LLQAYDTEKG AGTMSPYTML RTIGPEPWNV AYVEPSRRPA 70 80 90 100 110 120 DGRYGENPNR LYQHHQFQVI MKPSPTNIQE LYLDSLRALG INPLEHDIRF VEDNWENPSL 130 140 150 160 170 180 GCAGLGWEVW LDGMEITQFT YFQQVGGLEA NPVSAEITYG LERLASYIQD KENVFDLEWV 190 200 210 220 230 240 EGFTYGDIFT QPEYEHSKYT FEVSDSAMLF ELFSTYEKEA DRALEENLVF PAYDYVLKCS 250 260 270 280 290 HTFNLLDARG AISVTERTGY IGRVRNLARK CAKKYYEERE KLGFPMLKNK EADHEQA

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB05089.1.
PIR	B83821.
RefSeq	NP_242236.1.
3D structure databases
ProteinModelPortal	Q9KD49.
SMR	Q9KD49. Positions 1-281.
ModBase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000053903; EBBACP00000052542; EBBACG00000053894.
GeneID	892317.
GenomeReviews	Gene locus BH1370 in contig BA000004_GR.
KEGG	bha:BH1370.
NMPDR	fig|272558.1.peg.1370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	Q9KD49.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1370-MONOMER.
BRENDA	6.1.1.14. 191865.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BACHD

Accession

Primary (citable) accession number: Q9KD49

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	October 1, 2000
Last modified:	August 10, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)