Q9KCX2 (MSRB_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	BH1447

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	143 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 143	143	Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400		PRO_0000140260
Sites
	Active site	116	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KCX2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: A6DA03609C308314	FASTA	143	16,299
	10 20 30 40 50 60 MTEQNEELKK KLTPLQYEVT QNNGTEPPFR NEYYDLEAEG IYVDIVSGKP LFSSKDKYDA 70 80 90 100 110 120 GCGWPSFTKP IDEEEVIEKE DRSHGMFRTE VRSKQADSHL GHVFPDGPGP NGLRYCINSA 130 140 ALRFIPKADL EKEGYGKYKA LFD

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB05166.1.
PIR	G83830.
RefSeq	NP_242313.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9KCX2.
SMR	Q9KCX2. Positions 1-143.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050884; EBBACP00000049523; EBBACG00000050875.
GeneID	890674.
GenomeReviews	Gene locus BH1447 in contig BA000004_GR.
KEGG	bha:BH1447.
NMPDR	fig|272558.1.peg.1447.
PATRIC	18939989. VBIBacHal18977_1508.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000000580.
HOGENOM	HBG715255.
OMA	FTDGPVD.
PhylomeDB	Q9KCX2.
ProtClustDB	PRK00222.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1447-MONOMER.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_BACHD

Accession

Primary (citable) accession number: Q9KCX2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program