Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9KCB7 (AROC_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Synonyms:aroF
Ordered Locus Names:BH1656
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390Chorismate synthase HAMAP MF_00300
PRO_0000140548

Sequences

Sequence LengthMass (Da)Tools
Q9KCB7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B4A04FD52E9ABA60

FASTA39042,401
        10         20         30         40         50         60 
MRYLTAGESH GPQLTTIIEG APAQLELVAD DINVDLARRQ GGHGRGRRMQ IEKDQVQIVG 

        70         80         90        100        110        120 
GIRHGKTTGA PIALVVENKD WKHWTKIMGA EPLTGDEEKE IKRKITRPRP GHADLNGAIK 

       130        140        150        160        170        180 
YGHRDMRNVL ERSSARETTV RVAAGAVAKK ILRTFGIEVG SHVLEIGGVK AEKTSYDQLS 

       190        200        210        220        230        240 
NLKELAEASP VRCLDKEAEQ EMIAAIDQAK ENGDSIGGVV EVIVEGVPIG LGSHVHYDRK 

       250        260        270        280        290        300 
LDAKIAAAVM SINAFKGVEF GIGFEAASKP GSEVHDEIAW DEERGYYRKS NNLGGFEGGM 

       310        320        330        340        350        360 
TNGMPIVVRG VMKPIPTLYK PLQSVDIATK EPFAASIERS DSCAVPAAAV VAEAVVAWEV 

       370        380        390 
ANALLERFGA DQVEEIEKNI REFNEKARLF

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000004 Genomic DNA. Translation: BAB05375.1.
PIRH83856.
RefSeqNP_242522.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9KCB7.
SMRQ9KCB7. Positions 1-380.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000053612; EBBACP00000052251; EBBACG00000053603.
GeneID894147.
GenomeReviewsGene locus BH1656 in contig BA000004_GR.
KEGGbha:BH1656.
NMPDRfig|272558.1.peg.1656.
PATRIC18940430. VBIBacHal18977_1728.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000002373.
HOGENOMHBG292336.
OMAMLRWLTA.
PhylomeDBQ9KCB7.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycBHAL272558:BH1656-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_BACHD
AccessionPrimary (citable) accession number: Q9KCB7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents