ID   Q9KBU7_HALH5            Unreviewed;       678 AA.
AC   Q9KBU7;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAB05546.1};
GN   Name=mcpC {ECO:0000313|EMBL:BAB05546.1};
OS   Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC   Halalkalibacterium (ex Joshi et al. 2022).
OX   NCBI_TaxID=272558 {ECO:0000313|EMBL:BAB05546.1, ECO:0000313|Proteomes:UP000001258};
RN   [1] {ECO:0000313|EMBL:BAB05546.1, ECO:0000313|Proteomes:UP000001258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125
RC   {ECO:0000313|Proteomes:UP000001258};
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BA000004; BAB05546.1; -; Genomic_DNA.
DR   PIR; C83878; C83878.
DR   RefSeq; WP_010897988.1; NC_002570.2.
DR   AlphaFoldDB; Q9KBU7; -.
DR   STRING; 272558.gene:10727725; -.
DR   KEGG; bha:BH1827; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 9760371at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001258};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          313..365
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          384..641
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   678 AA;  75158 MW;  EFB6E8FC1B537AF3 CRC64;
     MAKSIKWKLI VTTSGLIGLI VFAILGTMYV QASKETQTST ESEAGRVTIE MEKLLDYYLP
     FFSSAVDRLA QDRAVMTFLR SNPDDESFPD EINEEFVYFL ENDERADLFY IGQQSNGNFY
     SYPEVELPDD YDPRARPWYE KAAETPEQVV WSEPYLSATV GHEVMMVTVA KAIVDPRNQQ
     LLGVVAIDIL LDDLSQLLNE TEVGMGGSLA LIHESGMVIA HPDADLRGEN LSDESFIQDL
     QQAQGKQGQI EYEFENEART LFFNKMDQMD WNIVAFYRDK EVTAPVRQLR NYFILVLLVS
     MTIATATSYY FGRKMANPIL ALNDRMQQVI KGDLTASADV KSQDEIGQLS DGFNQMVQTL
     REMIHALRQT GATSNKEAVE LRSMLQEAIA SSEEVATSST AVANGAVDQA EEIEHAKSDI
     EKLSAQIDWM DQTASQINEL AASTANVSAS GLEQVETLRE KTEEHERIIQ KMEGIVNHFV
     HQTEEILSIV ELIQSFSEQT NLLALNASIE AARAGEYGKG FSVVAEEIRK LAEQSTKATN
     NIQSAVQKIK ESGAHATEEM TKTAAQSAEQ VKRVDQSIAS FTHISSNIEQ VVNSIKTVVK
     QLQTMNESRN QAVLAINNIA GTSQDTAAAA EQISASIEEL VNVLNTIGTS SERLNTLSDD
     LNKQAKAFKV QSTDDVES
//