Reviewed, UniProtKB/Swiss-Prot Q9KBQ4 (ARAD_BACHD)

Names and origin

Protein names

Recommended name:
    L-ribulose-5-phosphate 4-epimerase
    EC=5.1.3.4
Alternative name(s):
    Phosphoribulose isomerase

Gene names

Name:	araD
Ordered Locus Names:	BH1871

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-ribulose 5-phosphate = D-xylulose 5-phosphate.
Cofactor	Binds 1 zinc ion per subunit Potential.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 3/3.
Sequence similarities	Belongs to the aldolase class II family. AraD/fucA subfamily.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Metal-binding Zinc
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	L-ribulose-phosphate 4-epimerase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	L-ribulose-5-phosphate 4-epimerase		PRO_0000162916
Sites
	Metal binding	75	1	Zinc By similarity
	Metal binding	94	1	Zinc By similarity
	Metal binding	96	1	Zinc By similarity
	Metal binding	168	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KBQ4-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 6CA570D2A6B4DB97	FASTA	231	25,991
	10 20 30 40 50 60 MLEQLKETVF KANLYLPKYQ LVTFTWGNVS GIDREKGLVV IKPSGVEYFE MKSKDMVVVD 70 80 90 100 110 120 LEGNIVEGDL KPSSDTPTHL ALYRAFDKVG GIVHTHSVWA TAWAQAGKEI PAYGTTHADY 130 140 150 160 170 180 FHGTIPCTRP MTETEILGDY EKETGNVIVE TFRNKDPMSI PGVLVHSHAP FVWGKDPMEA 190 200 210 220 230 VHHAVVLEEV AKMAQKTLSI SERTLPMDSV LLDRHFYRKH GQAAYYGQEK R

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000004 Genomic DNA. Translation: BAB05590.1.
PIR	G83883.
RefSeq	NP_242737.1.
3D structure databases
HSSP	HSSP built from PDB template 1JDI based on UniProtKB P08203.
ModBase	Search...
Genome annotation databases
GeneID	891374.
GenomeReviews	Gene locus BH1871 in contig BA000004_GR.
KEGG	bha:BH1871.
NMPDR	fig|272558.1.peg.1871.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9KBQ4.
OMA	ISKDRSY.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1871-MON.
BRENDA	5.1.3.4. 191865.
Family and domain databases
InterPro	IPR001303. Aldolase_II/adducin_N. IPR004661. AraD. [Graphical view]
Gene3D	G3DSA:3.40.225.10. Aldolase_II/adducin_N. 1 hit.
Pfam	PF00596. Aldolase_II. 1 hit. [Graphical view]
TIGRFAMs	TIGR00760. araD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAD_BACHD

Accession

Primary (citable) accession number: Q9KBQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2002
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)