Q9KBQ2 (ARAA_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
L-arabinose isomerase
EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	BH1873

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	497 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: EC L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 497	497	L-arabinose isomerase HAMAP MF_00519		PRO_0000198379
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	331	1	Manganese By similarity
	Metal binding	348	1	Manganese By similarity
	Metal binding	447	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9KBQ2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 637D660D25E3F5A4	FASTA	497	56,320
	10 20 30 40 50 60 MLQTKPYTFW FITGSQHLYG EDAIEQVRQH SQTMVEKLNK IGELPYTIEL KEVLTTPDAI 70 80 90 100 110 120 RKMVIAANSD DDCAGMITWM HTFSPAKMWI NGLKQLKKPL LHLHTQFNRE IPYDDIDMDF 130 140 150 160 170 180 MNLNQSAHGD REYGHIGARL NISRKVIVGH WQNNDVQERL GAWMRTAAAF VDGHHLKVAR 190 200 210 220 230 240 FGDNMREVAV TEGDKVEAQI QFGWSITAFG IGDLVEKMKA VSEDEVRRLF DEYQELYRLS 250 260 270 280 290 300 PSILEQDEVK AAVLEQAKME LALKEFLEEG GYTAFTTNFE DLHGMKQLPG LAVQRLMAEG 310 320 330 340 350 360 YGFGGEGDWK TAALLRMMKI IADGKGTSFM EDYTYHLAEG NELVLGSHML EICPTIAANQ 370 380 390 400 410 420 PEIQVHPLGI GGKEDPARLV FDGADGPALN ASLIDLGHRF RLVVNEVEAI KPERDMPKLP 430 440 450 460 470 480 VAKVLWKCKP SLSEATEAWI HAGGAHHTVF SFEVTPEQLY DWATLADIEV VFINDKTDVL 490 QFQQQLQWNE AFRRLFK

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB05592.1.
PIR	A83884.
RefSeq	NP_242739.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9KBQ2.
SMR	Q9KBQ2. Positions 1-495.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050669; EBBACP00000049308; EBBACG00000050660.
GeneID	892470.
GenomeReviews	Gene locus BH1873 in contig BA000004_GR.
KEGG	bha:BH1873.
NMPDR	fig|272558.1.peg.1873.
PATRIC	18940876. VBIBacHal18977_1951.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000001793.
HOGENOM	HBG297198.
OMA	EVCPTIA.
PhylomeDB	Q9KBQ2.
ProtClustDB	PRK02929.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1873-MONOMER.
BRENDA	5.3.1.4. 661.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAA_BACHD

Accession

Primary (citable) accession number: Q9KBQ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program