Q9K9Q6 (COAD_BACHD) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 71.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphopantetheine adenylyltransferase EC=2.7.7.3 Alternative name(s): Dephospho-CoA pyrophosphorylase Pantetheine-phosphate adenylyltransferase Short name=PPAT | ||||||
| Gene names |
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| Organism | Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 272558 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 165 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151 |
| Catalytic activity | ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151 |
| Pathway | Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151 |
| Subunit structure | Homohexamer By similarity. HAMAP MF_00151 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00151. |
| Sequence similarities | Belongs to the bacterial CoaD family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Coenzyme A biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | coenzyme A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantetheine-phosphate adenylyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 165 | 165 | Phosphopantetheine adenylyltransferase HAMAP MF_00151 | PRO_0000156166 | |||
Sequences
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References
| [1] | "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000004 Genomic DNA. Translation: BAB06308.1. |
| PIR | E83973. |
| RefSeq | NP_243455.1. NC_002570.2. |
3D structure databases | |
| ProteinModelPortal | Q9K9Q6. |
| SMR | Q9K9Q6. Positions 3-158. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000050373; EBBACP00000049012; EBBACG00000050364. |
| GeneID | 890981. |
| GenomeReviews | Gene locus BH2589 in contig BA000004_GR. |
| KEGG | bha:BH2589. |
| NMPDR | fig|272558.1.peg.2589. |
| PATRIC | 18942372. VBIBacHal18977_2699. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000002538. |
| HOGENOM | HBG288308. |
| OMA | AMSDFEY. |
| PhylomeDB | Q9K9Q6. |
| ProtClustDB | CLSK2749304. |
Enzyme and pathway databases | |
| BioCyc | BHAL272558:BH2589-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00151. PPAT_bact. [Tree] |
| InterPro | IPR004821. Cyt_trans-rel. IPR004820. Cytidylyltransf. IPR001980. LPS_biosynth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit. |
| KO | K00954. |
| Pfam | PF01467. CTP_transf_2. 1 hit. [Graphical view] |
| PRINTS | PR01020. LPSBIOSNTHSS. |
| TIGRFAMs | TIGR01510. CoaD_prev_kdtB. 1 hit. TIGR00125. Cyt_tran_rel. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | COAD_BACHD | ||||||||
| Accession | Primary (citable) accession number: Q9K9Q6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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