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Q9K9L8 (GLSA1_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase 1

EC=3.5.1.2
Gene names
Name:glsA1
Ordered Locus Names:BH2627
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Glutaminase 1 HAMAP-Rule MF_00313
PRO_0000110592

Sites

Binding site641Substrate By similarity
Binding site1161Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2441Substrate By similarity
Binding site2621Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K9L8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B8D3F17E16514590

FASTA30833,456
        10         20         30         40         50         60 
MWKQDETLEQ IVLECKKYTE EGTVASYIPA LAKADVSTLG IAIYRGGDEQ VIAGDADEKF 

        70         80         90        100        110        120 
TLQSISKVIA LALALLDVGE EAVFSKVGME PTGDPFNSIS KLETSVPSKP LNPMINAGAL 

       130        140        150        160        170        180 
AVTNMIIGET TEQSLGRLLS FIHELTKNPT ITYNLEVAQS EFDTAFLNRS LSYFLKQHGV 

       190        200        210        220        230        240 
IQADVEQLLD LYTKQCAIEM CCSDLARIGY VFANEGRDPD TGQRIVPLHV ARIIKTFMVT 

       250        260        270        280        290        300 
CGMYNASGEF AIRVGIPAKS GVSGAILALV PNKYGIAVYS PALDEKGNSL AGIKLLETLS 


CREEWSIF 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB06346.1.
PIRC83978.
RefSeqNP_243493.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K9L8.
SMRQ9K9L8. Positions 6-308.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH2627.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB06346; BAB06346; BAB06346.
GeneID892523.
KEGGbha:BH2627.
PATRIC18942442. VBIBacHal18977_2734.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-2711-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA1_BACHD
AccessionPrimary (citable) accession number: Q9K9L8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families