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Q9K9D1 (GLSA2_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase 2

EC=3.5.1.2
Gene names
Name:glsA2
Ordered Locus Names:BH2717
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 324324Glutaminase 2 HAMAP-Rule MF_00313
PRO_0000110593

Sites

Binding site751Substrate By similarity
Binding site1271Substrate By similarity
Binding site1711Substrate By similarity
Binding site1781Substrate By similarity
Binding site2021Substrate By similarity
Binding site2541Substrate By similarity
Binding site2721Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K9D1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 03B9D3F716B01474

FASTA32435,506
        10         20         30         40         50         60 
MLQQKQSLLE HKPVLSKELE KLVNHYRTLS LNGQCAQYIP ALREANQTYL GLYVVHSNGI 

        70         80         90        100        110        120 
EIKSGDWQVP FTLQSISKII NFIAACLDRG ITYVLDRVDV EPTGDPFNSM VRLEMRKTGK 

       130        140        150        160        170        180 
PFNPMINAGA ITVASLLSGK SPTEKLESVY SLVEKMLGRR ASANEAVFHS EWQTAHRNRS 

       190        200        210        220        230        240 
LAYYLKDTGY LESEVDDALH VYFTLCAIEV ATKDIAKIGL ILANNGYDPL SHQQIFPKEV 

       250        260        270        280        290        300 
AKLTKALMLT CGMYNASGTF AAHIGIPAKS GVSGGIMAAV PARGRSDEAM GIGIYGPAID 

       310        320 
DFGNSVAGVA LLKHLSHMWD LSIF 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB06436.1.
PIRE83989.
RefSeqNP_243583.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K9D1.
SMRQ9K9D1. Positions 28-324.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH2717.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB06436; BAB06436; BAB06436.
GeneID893579.
KEGGbha:BH2717.
PATRIC18942620. VBIBacHal18977_2823.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMASANYIPA.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-2801-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA2_BACHD
AccessionPrimary (citable) accession number: Q9K9D1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families