Q9K9D1 (GLSA2_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutaminase 2
EC=3.5.1.2

Gene names

Name:	glsA2
Ordered Locus Names:	BH2717

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus halodurans

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the glutaminase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 324	324	Glutaminase 2 HAMAP-Rule MF_00313		PRO_0000110593
Sites
	Binding site	75	1	Substrate By similarity
	Binding site	127	1	Substrate By similarity
	Binding site	171	1	Substrate By similarity
	Binding site	178	1	Substrate By similarity
	Binding site	202	1	Substrate By similarity
	Binding site	254	1	Substrate By similarity
	Binding site	272	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9K9D1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 03B9D3F716B01474	FASTA	324	35,506
	10 20 30 40 50 60 MLQQKQSLLE HKPVLSKELE KLVNHYRTLS LNGQCAQYIP ALREANQTYL GLYVVHSNGI 70 80 90 100 110 120 EIKSGDWQVP FTLQSISKII NFIAACLDRG ITYVLDRVDV EPTGDPFNSM VRLEMRKTGK 130 140 150 160 170 180 PFNPMINAGA ITVASLLSGK SPTEKLESVY SLVEKMLGRR ASANEAVFHS EWQTAHRNRS 190 200 210 220 230 240 LAYYLKDTGY LESEVDDALH VYFTLCAIEV ATKDIAKIGL ILANNGYDPL SHQQIFPKEV 250 260 270 280 290 300 AKLTKALMLT CGMYNASGTF AAHIGIPAKS GVSGGIMAAV PARGRSDEAM GIGIYGPAID 310 320 DFGNSVAGVA LLKHLSHMWD LSIF

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB06436.1.
PIR	E83989.
RefSeq	NP_243583.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9K9D1.
SMR	Q9K9D1. Positions 28-324.
ModBase	Search...
Protein-protein interaction databases
STRING	272558.BH2717.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB06436; BAB06436; BAB06436.
GeneID	893579.
KEGG	bha:BH2717.
PATRIC	18942620. VBIBacHal18977_2823.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2066.
HOGENOM	HOG000216890.
KO	K01425.
OMA	CKITLAI.
ProtClustDB	PRK12357.
Enzyme and pathway databases
BioCyc	BHAL272558:GJC5-2801-MONOMER.
Family and domain databases
Gene3D	3.40.710.10. 1 hit.
HAMAP	MF_00313. Glutaminase.
InterPro	IPR012338. Beta-lactam/transpept-like. IPR015868. Glutaminase. [Graphical view]
PANTHER	PTHR12544. PTHR12544. 1 hit.
Pfam	PF04960. Glutaminase. 1 hit. [Graphical view]
SUPFAM	SSF56601. PBP_transp_fold. 1 hit.
TIGRFAMs	TIGR03814. Gln_ase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLSA2_BACHD

Accession

Primary (citable) accession number: Q9K9D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program