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Protein

Glutaminase 2

Gene

glsA2

Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei75SubstrateUniRule annotation1
Binding sitei127SubstrateUniRule annotation1
Binding sitei171SubstrateUniRule annotation1
Binding sitei178SubstrateUniRule annotation1
Binding sitei202SubstrateUniRule annotation1
Binding sitei254SubstrateUniRule annotation1
Binding sitei272Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 2UniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsA2UniRule annotation
Ordered Locus Names:BH2717
OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Taxonomic identifieri272558 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001258 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001105931 – 324Glutaminase 2Add BLAST324

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi272558.BH2717.

Structurei

3D structure databases

ProteinModelPortaliQ9K9D1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiLACEVEE.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9K9D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQQKQSLLE HKPVLSKELE KLVNHYRTLS LNGQCAQYIP ALREANQTYL
60 70 80 90 100
GLYVVHSNGI EIKSGDWQVP FTLQSISKII NFIAACLDRG ITYVLDRVDV
110 120 130 140 150
EPTGDPFNSM VRLEMRKTGK PFNPMINAGA ITVASLLSGK SPTEKLESVY
160 170 180 190 200
SLVEKMLGRR ASANEAVFHS EWQTAHRNRS LAYYLKDTGY LESEVDDALH
210 220 230 240 250
VYFTLCAIEV ATKDIAKIGL ILANNGYDPL SHQQIFPKEV AKLTKALMLT
260 270 280 290 300
CGMYNASGTF AAHIGIPAKS GVSGGIMAAV PARGRSDEAM GIGIYGPAID
310 320
DFGNSVAGVA LLKHLSHMWD LSIF
Length:324
Mass (Da):35,506
Last modified:October 1, 2000 - v1
Checksum:i03B9D3F716B01474
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000004 Genomic DNA. Translation: BAB06436.1.
PIRiE83989.
RefSeqiWP_010898865.1. NC_002570.2.

Genome annotation databases

EnsemblBacteriaiBAB06436; BAB06436; BAB06436.
KEGGibha:BH2717.
PATRICi18942620. VBIBacHal18977_2823.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000004 Genomic DNA. Translation: BAB06436.1.
PIRiE83989.
RefSeqiWP_010898865.1. NC_002570.2.

3D structure databases

ProteinModelPortaliQ9K9D1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272558.BH2717.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB06436; BAB06436; BAB06436.
KEGGibha:BH2717.
PATRICi18942620. VBIBacHal18977_2823.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiLACEVEE.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA2_BACHD
AccessioniPrimary (citable) accession number: Q9K9D1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.