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Q9K9C6

- BGAL_BACHD

UniProt

Q9K9C6 - BGAL_BACHD

Protein

Beta-galactosidase

Gene

lacZ

Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei460 – 4601Proton donorBy similarity
    Active sitei527 – 5271NucleophileBy similarity

    GO - Molecular functioni

    1. beta-galactosidase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciBHAL272558:GJC5-2807-MONOMER.

    Protein family/group databases

    CAZyiGH2. Glycoside Hydrolase Family 2.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-galactosidase (EC:3.2.1.23)
    Short name:
    Beta-gal
    Alternative name(s):
    Lactase
    Gene namesi
    Name:lacZ
    Ordered Locus Names:BH2723
    OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
    Taxonomic identifieri272558 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001258: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. beta-galactosidase complex Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10141014Beta-galactosidasePRO_0000057658Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272558.BH2723.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9K9C6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 2 family.Curated

    Phylogenomic databases

    eggNOGiCOG3250.
    HOGENOMiHOG000252444.
    KOiK01190.
    OMAiDPKKPYI.
    OrthoDBiEOG6XWV0T.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    2.60.40.320. 2 hits.
    2.70.98.10. 1 hit.
    3.20.20.80. 1 hit.
    InterProiIPR004199. B-gal_small/dom_5.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR008979. Galactose-bd-like.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR006101. Glyco_hydro_2.
    IPR013812. Glyco_hydro_2/20_Ig-like.
    IPR023232. Glyco_hydro_2_AS.
    IPR023230. Glyco_hydro_2_CS.
    IPR006102. Glyco_hydro_2_Ig-like.
    IPR006104. Glyco_hydro_2_N.
    IPR006103. Glyco_hydro_2_TIM.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02929. Bgal_small_N. 1 hit.
    PF00703. Glyco_hydro_2. 1 hit.
    PF02836. Glyco_hydro_2_C. 1 hit.
    PF02837. Glyco_hydro_2_N. 1 hit.
    [Graphical view]
    PRINTSiPR00132. GLHYDRLASE2.
    SMARTiSM01038. Bgal_small_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF49303. SSF49303. 2 hits.
    SSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF74650. SSF74650. 1 hit.
    PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
    PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9K9C6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTHSNVSWL RDVNVFAVNR LPAHSDHVYY ETVEEAKKEP PMSMRHSLNG     50
    HWKFHYAINP NTRPKEFYQL GFDCKCWDDI LVPGHIQLQG YGKPQYVNTM 100
    YPWDGHHHLR PPEIPEDDNP VGSYVKYFDI PNNMSNHPLF ISFQGVETAF 150
    YVWLNGEFVG YSEDSFTPAE FDLTPYAVEG ENKLCVEVYQ RSTGSWLEDQ 200
    DFWRFSGIFR DVYLYTIPNI HVYDMHVRAD LDRSLQTGIL ETTLELKRSQ 250
    EKEVMIVAEL YDAEGAVVAT ADMKTNQDQA TVSMSVDSPA LWSAEDPYLY 300
    KLFLKLFDEN GTLVEVVPQK IGFRRFELVN NIMTLNGKRI VFKGVNRHEF 350
    NGRTGRVVTK EDMLEDIKTM KKHNINAVRT SHYPNNSEWY QLCDEYGLYV 400
    IDEMNLETHG SWQKLGKVEP SWNIPGNHLE WEPIVMDRAV SMFERDKNHP 450
    SILIWSCGNE SYAGEVILNV SRYFKSVDPS RLVHYEGVFH ARAYDATSDM 500
    ESRMYAKPKD IEDYLTNDPK KPYISCEYMH AMGNSLGGMH KYTELEQKYP 550
    MYQGGFIWDY IDQALLKKDR YGKEYFAYGG DFGDRPTDYS FCANGIVYAD 600
    RKPSPKMQEV KFLYQNIKLV PDREGVLVKN ENLFTDTSAY QLEYVLYWEG 650
    TELYRKKQDV FVAPQEEVYL PFDWLEQGMN ESGEYCIHTM LTLKQDQLWA 700
    EKGHEVAFGQ HVYRMGAIQK ERNARGALKV VHGDVNIGIH GEDFSVLFSK 750
    AVGSLVSLHY AGKEMIEQPP MPLFWRATTD NDKGCSQLYH SGIWYAASLA 800
    RKCVNMEVEE KPGHVSVLFT YHFAISDRVE VKVGYTVFPD GSLRVRSTYQ 850
    ASKGGETLPQ LPMFALSFKL PADYEQLEWY ALGPEENYAD RATGARLCTF 900
    KNKVEDSLSQ YVTPQESGNR TGVRTVKILD ANGQGIEVCS VEEPIECQIS 950
    PYTAFELEQA SHPYELPNVH YTVVNVAGKQ MGVGGDDSWG APVHDEYVLK 1000
    ADQDLEFVFD INRV 1014
    Length:1,014
    Mass (Da):116,656
    Last modified:October 1, 2000 - v1
    Checksum:i30405EB697C72798
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000004 Genomic DNA. Translation: BAB06442.1.
    PIRiC83990.
    RefSeqiNP_243589.1. NC_002570.2.

    Genome annotation databases

    EnsemblBacteriaiBAB06442; BAB06442; BAB06442.
    GeneIDi893545.
    KEGGibha:BH2723.
    PATRICi18942632. VBIBacHal18977_2829.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000004 Genomic DNA. Translation: BAB06442.1 .
    PIRi C83990.
    RefSeqi NP_243589.1. NC_002570.2.

    3D structure databases

    ProteinModelPortali Q9K9C6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272558.BH2723.

    Protein family/group databases

    CAZyi GH2. Glycoside Hydrolase Family 2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB06442 ; BAB06442 ; BAB06442 .
    GeneIDi 893545.
    KEGGi bha:BH2723.
    PATRICi 18942632. VBIBacHal18977_2829.

    Phylogenomic databases

    eggNOGi COG3250.
    HOGENOMi HOG000252444.
    KOi K01190.
    OMAi DPKKPYI.
    OrthoDBi EOG6XWV0T.

    Enzyme and pathway databases

    BioCyci BHAL272558:GJC5-2807-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    2.60.40.320. 2 hits.
    2.70.98.10. 1 hit.
    3.20.20.80. 1 hit.
    InterProi IPR004199. B-gal_small/dom_5.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR008979. Galactose-bd-like.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR006101. Glyco_hydro_2.
    IPR013812. Glyco_hydro_2/20_Ig-like.
    IPR023232. Glyco_hydro_2_AS.
    IPR023230. Glyco_hydro_2_CS.
    IPR006102. Glyco_hydro_2_Ig-like.
    IPR006104. Glyco_hydro_2_N.
    IPR006103. Glyco_hydro_2_TIM.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02929. Bgal_small_N. 1 hit.
    PF00703. Glyco_hydro_2. 1 hit.
    PF02836. Glyco_hydro_2_C. 1 hit.
    PF02837. Glyco_hydro_2_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00132. GLHYDRLASE2.
    SMARTi SM01038. Bgal_small_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49303. SSF49303. 2 hits.
    SSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF74650. SSF74650. 1 hit.
    PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
    PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
      Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
      Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

    Entry informationi

    Entry nameiBGAL_BACHD
    AccessioniPrimary (citable) accession number: Q9K9C6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 10, 2002
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3