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Q9K9C6 (BGAL_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase

Short name=Beta-gal
EC=3.2.1.23
Alternative name(s):
Lactase
Gene names
Name:lacZ
Ordered Locus Names:BH2723
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length1014 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sequence similarities

Belongs to the glycosyl hydrolase 2 family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10141014Beta-galactosidase
PRO_0000057658

Sites

Active site4601Proton donor By similarity
Active site5271Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K9C6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 30405EB697C72798

FASTA1,014116,656
        10         20         30         40         50         60 
MKTHSNVSWL RDVNVFAVNR LPAHSDHVYY ETVEEAKKEP PMSMRHSLNG HWKFHYAINP 

        70         80         90        100        110        120 
NTRPKEFYQL GFDCKCWDDI LVPGHIQLQG YGKPQYVNTM YPWDGHHHLR PPEIPEDDNP 

       130        140        150        160        170        180 
VGSYVKYFDI PNNMSNHPLF ISFQGVETAF YVWLNGEFVG YSEDSFTPAE FDLTPYAVEG 

       190        200        210        220        230        240 
ENKLCVEVYQ RSTGSWLEDQ DFWRFSGIFR DVYLYTIPNI HVYDMHVRAD LDRSLQTGIL 

       250        260        270        280        290        300 
ETTLELKRSQ EKEVMIVAEL YDAEGAVVAT ADMKTNQDQA TVSMSVDSPA LWSAEDPYLY 

       310        320        330        340        350        360 
KLFLKLFDEN GTLVEVVPQK IGFRRFELVN NIMTLNGKRI VFKGVNRHEF NGRTGRVVTK 

       370        380        390        400        410        420 
EDMLEDIKTM KKHNINAVRT SHYPNNSEWY QLCDEYGLYV IDEMNLETHG SWQKLGKVEP 

       430        440        450        460        470        480 
SWNIPGNHLE WEPIVMDRAV SMFERDKNHP SILIWSCGNE SYAGEVILNV SRYFKSVDPS 

       490        500        510        520        530        540 
RLVHYEGVFH ARAYDATSDM ESRMYAKPKD IEDYLTNDPK KPYISCEYMH AMGNSLGGMH 

       550        560        570        580        590        600 
KYTELEQKYP MYQGGFIWDY IDQALLKKDR YGKEYFAYGG DFGDRPTDYS FCANGIVYAD 

       610        620        630        640        650        660 
RKPSPKMQEV KFLYQNIKLV PDREGVLVKN ENLFTDTSAY QLEYVLYWEG TELYRKKQDV 

       670        680        690        700        710        720 
FVAPQEEVYL PFDWLEQGMN ESGEYCIHTM LTLKQDQLWA EKGHEVAFGQ HVYRMGAIQK 

       730        740        750        760        770        780 
ERNARGALKV VHGDVNIGIH GEDFSVLFSK AVGSLVSLHY AGKEMIEQPP MPLFWRATTD 

       790        800        810        820        830        840 
NDKGCSQLYH SGIWYAASLA RKCVNMEVEE KPGHVSVLFT YHFAISDRVE VKVGYTVFPD 

       850        860        870        880        890        900 
GSLRVRSTYQ ASKGGETLPQ LPMFALSFKL PADYEQLEWY ALGPEENYAD RATGARLCTF 

       910        920        930        940        950        960 
KNKVEDSLSQ YVTPQESGNR TGVRTVKILD ANGQGIEVCS VEEPIECQIS PYTAFELEQA 

       970        980        990       1000       1010 
SHPYELPNVH YTVVNVAGKQ MGVGGDDSWG APVHDEYVLK ADQDLEFVFD INRV 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB06442.1.
PIRC83990.
RefSeqNP_243589.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K9C6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH2723.

Protein family/group databases

CAZyGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB06442; BAB06442; BAB06442.
GeneID893545.
KEGGbha:BH2723.
PATRIC18942632. VBIBacHal18977_2829.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3250.
HOGENOMHOG000252444.
KOK01190.
OMADPKKPYI.
OrthoDBEOG6XWV0T.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-2807-MONOMER.

Family and domain databases

Gene3D2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSPR00132. GLHYDRLASE2.
SMARTSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGAL_BACHD
AccessionPrimary (citable) accession number: Q9K9C6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries