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Q9K997 (DCTS_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable C4-dicarboxylate sensor kinase
EC=2.7.13.3
Gene names
Name:dctS
Ordered Locus Names:BH2752
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Member of the two-component regulatory system dctS/dctR. Probably activates dctR by phosphorylation. Essential for expression of dctP By similarity.

Catalytic activity

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Contains 1 histidine kinase domain.

Contains 1 PAS (PER-ARNT-SIM) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 532532Probable C4-dicarboxylate sensor kinase
PRO_0000074727

Regions

Topological domain1 – 1212Cytoplasmic Potential
Transmembrane13 – 3321Helical; Potential
Topological domain34 – 175142Extracellular Potential
Transmembrane176 – 19621Helical; Potential
Topological domain197 – 532336Cytoplasmic Potential
Domain216 – 27964PAS
Domain315 – 531217Histidine kinase

Amino acid modifications

Modified residue3391Phosphohistidine; by autocatalysis By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K997 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 5C2445CEA0119A12

FASTA53259,999
        10         20         30         40         50         60 
MRLFRQLSIQ WKITILSFGI VAFALMMVSI SLLGYVTSIK EDELSNRTMI TAQLVAQNHT 

        70         80         90        100        110        120 
VQQWVDAKPE EASRTLQPIV ERIRVINDHD YIVLLNMDRI RITHPIPERL QTPFVGGDED 

       130        140        150        160        170        180 
PAFAEHIYLS KAKTEGVVTV RAFMPILNQQ REQVGVAVVG SVLPSYADMI QEFWQPALLI 

       190        200        210        220        230        240 
GLITALFGFW GSWLLASHIK RQTFNMEPDE LAHLLVERDA SFNAIHEGVV AINKHEKITI 

       250        260        270        280        290        300 
MNEAARRMLG VKEKAIGRNI HEVIPDTKLP EILSIGKPLY QREFYIQGRL VFSNRIPIQI 

       310        320        330        340        350        360 
DGETVGAIAI FQDKSDVDRL AEELTGVQAF VDALRVQNHE YSNKLHTIAG LIQLDEGKKA 

       370        380        390        400        410        420 
LQYIFDLEEE QEEFSGVVMQ KIHNDSLAGL LLGKVSRGKE LGVQVIIEKD SEFIDHPEGV 

       430        440        450        460        470        480 
TTHDLVVIVG NLIDNSLDAF SSTQDQNKTV HVFIGEENDF LKIRVRDNGE GIREEVREKM 

       490        500        510        520        530 
FVRGFSTKST SGRGIGLFLI QAIVERVEGK IEVESELNIG TTFSIYLPKK RG

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References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000004 Genomic DNA. Translation: BAB06471.1.
PIRH83993.
RefSeqNP_243618.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K997.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000051012; EBBACP00000049651; EBBACG00000051003.
GeneID893487.
GenomeReviewsGene locus BH2752 in contig BA000004_GR.
KEGGbha:BH2752.
NMPDRfig|272558.1.peg.2752.
PATRIC18942688. VBIBacHal18977_2856.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000000017.
HOGENOMHBG537380.
OMASNRIPIQ.
PhylomeDBQ9K997.
ProtClustDBCLSK873412.

Enzyme and pathway databases

BioCycBHAL272558:BH2752-MONOMER.

Family and domain databases

InterProIPR003594. ATPase-like_ATP-bd.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR004358. Sig_transdc_His_kin-like_C.
IPR016120. Sig_transdc_His_kin_SpoOB.
IPR005467. Sig_transdc_His_kinase_core.
IPR016121. Spore_sensor_kin_SpoOB_hlx.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:1.10.287.130. Sensor_kinase_SpoOB-type_hlx. 1 hit.
KOK11691.
PfamPF02518. HATPase_c. 1 hit.
PF00989. PAS. 1 hit.
[Graphical view]
PRINTSPR00344. BCTRLSENSOR.
SMARTSM00387. HATPase_c. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF55890. Sensor_kinase_SpoOB-type. 1 hit.
PROSITEPS50109. HIS_KIN. 1 hit.
PS50112. PAS. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDCTS_BACHD
AccessionPrimary (citable) accession number: Q9K997
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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