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Q9K993 (XYLA_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase

EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:BH2757
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylopyranose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP-Rule MF_00455
PRO_0000195762

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K993 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D4EB48A9FCA2D24E

FASTA44049,967
        10         20         30         40         50         60 
MTFFNDVEKV QYEGPRSTNP YAFKYYNPEE IVAGKTMAEH LRFSIAYWHT FVGDGSDPFG 

        70         80         90        100        110        120 
VGTMQRPWDQ YSGMDLAKAR VEAAFEFFEK LNVPYFCFHD VDVAPEGETL ADTYKNLDEI 

       130        140        150        160        170        180 
VLMIKDYMKT SKTKLLWNTA NMFTHPRWIH GAATSPNADV YAYAAAKVKK GLEIGKELGA 

       190        200        210        220        230        240 
ENYVFWGGRE GYETLLNTNM KLELDNLARF FHMAVDYAKE IGFDAQFLIE PKPKEPTKHQ 

       250        260        270        280        290        300 
YDFDVATGIA FLKTHGLDEH FKFNIEANHA TLAGHTFEHE LHLARIHDML GSVDANQGDT 

       310        320        330        340        350        360 
LLGWDTDEFP TDLYTTTLAM YEILKNDGLG KGGLNFDAKV RRGSFEANDL FHAHIAGMDS 

       370        380        390        400        410        420 
FAIGLKVANQ LLEDRVLEDV IDNRYKSYQS GIGQKIANND TNLKELEAYA LSLGEIKHSS 

       430        440 
GQQERIKATL NQYLLRVNEY 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB06476.1.
PIRE83994.
RefSeqNP_243623.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K993.
SMRQ9K993. Positions 3-437.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH2757.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB06476; BAB06476; BAB06476.
GeneID893475.
KEGGbha:BH2757.
PATRIC18942700. VBIBacHal18977_2861.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMALFHAHIG.
OrthoDBEOG62NX4R.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-2843-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. SSF51658. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BACHD
AccessionPrimary (citable) accession number: Q9K993
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families