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Reviewed, UniProtKB/Swiss-Prot Q9K993 (XYLA_BACHD)

Last modified February 9, 2010. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: BH2757
OrganismBacillus halodurans [Complete proteome] [HAMAP]
Taxonomic identifier86665 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP MF_00455
PRO_0000195762

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q9K993-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D4EB48A9FCA2D24E

FASTA44049,967
        10         20         30         40         50         60 
MTFFNDVEKV QYEGPRSTNP YAFKYYNPEE IVAGKTMAEH LRFSIAYWHT FVGDGSDPFG 

        70         80         90        100        110        120 
VGTMQRPWDQ YSGMDLAKAR VEAAFEFFEK LNVPYFCFHD VDVAPEGETL ADTYKNLDEI 

       130        140        150        160        170        180 
VLMIKDYMKT SKTKLLWNTA NMFTHPRWIH GAATSPNADV YAYAAAKVKK GLEIGKELGA 

       190        200        210        220        230        240 
ENYVFWGGRE GYETLLNTNM KLELDNLARF FHMAVDYAKE IGFDAQFLIE PKPKEPTKHQ 

       250        260        270        280        290        300 
YDFDVATGIA FLKTHGLDEH FKFNIEANHA TLAGHTFEHE LHLARIHDML GSVDANQGDT 

       310        320        330        340        350        360 
LLGWDTDEFP TDLYTTTLAM YEILKNDGLG KGGLNFDAKV RRGSFEANDL FHAHIAGMDS 

       370        380        390        400        410        420 
FAIGLKVANQ LLEDRVLEDV IDNRYKSYQS GIGQKIANND TNLKELEAYA LSLGEIKHSS 

       430        440 
GQQERIKATL NQYLLRVNEY

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References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000004 Genomic DNA. Translation: BAB06476.1.
PIRE83994.
RefSeqNP_243623.1.

3D structure databases

SMRQ9K993. Positions 3-437.
ModBaseSearch...

Genome annotation databases

GeneID893475.
GenomeReviewsGene locus BH2757 in contig BA000004_GR.
KEGGbha:BH2757.
NMPDRfig|272558.1.peg.2757.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.
PhylomeDBQ9K993.

Enzyme and pathway databases

BioCycBHAL272558:BH2757-MONOMER.
BRENDA5.3.1.5. 191865.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_BACHD
AccessionPrimary (citable) accession number: Q9K993
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: October 1, 2000
Last modified: February 9, 2010
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents