Q9K904 (PPNK1_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1
Short name=Poly(P)/ATP NAD kinase 1
EC=2.7.1.23

Gene names

Name:	ppnK1
Ordered Locus Names:	BH2848

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361		PRO_0000120595

Sequences

	Sequence		Length	Mass (Da)
	Q9K904 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: F79B9A043C6CEB57	FASTA	265	29,872
	10 20 30 40 50 60 MRFTVTSRGD DVSNTLQQKI KRYLLDFGLT LDEQEPDIVI TVGGDGTLLH AFHRYTSRLE 70 80 90 100 110 120 DTAFVGIHTG HLGFYADWVP DEVEKLVIHI AKTPYQIVEY PLLEVVVRHT DESESKRLLA 130 140 150 160 170 180 LNECTVKSQE GSLVSNVEIK GDVFEVFRGD GLCISTPSGS TAYNKALGGA ILHPSLASIQ 190 200 210 220 230 240 ISEMASINNR VYRTIGSPLV LPQHHTCLIK PLNQVELQVT IDHFTLAYKR VKSIQCRVAE 250 260 EKIRFARFRP FPFWKRVKES FIGDS

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB06567.1.
PIR	H84005.
RefSeq	NP_243714.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9K904.
SMR	Q9K904. Positions 1-262.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050723; EBBACP00000049362; EBBACG00000050714.
GeneID	893237.
GenomeReviews	Gene locus BH2848 in contig BA000004_GR.
KEGG	bha:BH2848.
NMPDR	fig|272558.1.peg.2848.
PATRIC	18942918. VBIBacHal18977_2960.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002705.
HOGENOM	HBG314020.
OMA	TISFANC.
PhylomeDB	Q9K904.
ProtClustDB	PRK04885.
Enzyme and pathway databases
BioCyc	BHAL272558:BH2848-MONOMER.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPNK1_BACHD

Accession

Primary (citable) accession number: Q9K904

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 4, 2001
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program