ID   NTPA2_BACHD             Reviewed;         194 AA.
AC   Q9K8D9;
DT   30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   16-JUN-2009, entry version 42.
DE   RecName: Full=Nucleoside-triphosphatase 2;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase 2;
DE            Short=NTPase 2;
GN   OrderedLocusNames=BH3067;
OS   Bacillus halodurans.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=86665;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153;
RX   MEDLINE=20512582; PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N.,
RA   Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S.,
RA   Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus
RT   halodurans and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; BA000004; BAB06786.1; -; Genomic_DNA.
DR   PIR; C84033; C84033.
DR   RefSeq; NP_243933.1; -.
DR   HSSP; Q57679; 1B78.
DR   GeneID; 890587; -.
DR   GenomeReviews; BA000004_GR; BH3067.
DR   KEGG; bha:BH3067; -.
DR   NMPDR; fig|272558.1.peg.3067; -.
DR   HOGENOM; Q9K8D9; -.
DR   OMA; Q9K8D9; VYTADWA.
DR   BioCyc; BHAL272558:BH3067-MON; -.
DR   BRENDA; 3.6.1.15; 191865.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p-like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    194       Nucleoside-triphosphatase 2.
FT                                /FTId=PRO_0000178125.
SQ   SEQUENCE   194 AA;  21868 MW;  BBC5A0C4F19A04B3 CRC64;
     MKEWIVATKN KGKVAEFEAI LGKRGFSVKS LLDYPAIEDI EETGSTFNEN ATIKAEAIAE
     RFQRPVLADD SGLIIDALDG RPGIFSARYA GEEKDDQKNI EKVLRELQDI PWKARTARFH
     CSIALARPQA ETIVFEGTCE GYITTEPKGT GGFGYDPIFY VPSHDKTMAE LTQEEKNKLS
     HRYHALKQLD KWLD
//