Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9K848 (Q9K848_BACHD) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:citC EMBL BAB06878.1
Ordered Locus Names:BH3159 EMBL BAB06878.1
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP] EMBL BAB06878.1
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length422 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q9K848 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 6FF37DA3417AE722

FASTA42246,361
        10         20         30         40         50         60 
MANGEKIKVS AGVLEVPNNP IIPFIEGDGT GPDIWAAAHR VIDAAVEKAY NGEKKIVWKE 

        70         80         90        100        110        120 
ILAGEKAFNQ TGQWLPDETL ETIREYTIAI KGPLTTPVGG GIRSLNVALR QELDLYVCLR 

       130        140        150        160        170        180 
PVRYFNGVPS PVKRPEDTNM VIFRENSEDI YAGIEYQAGT DEVKKVINFL REEMGVKKIR 

       190        200        210        220        230        240 
FPETSGIGIK PVSQEGTDRL VRAAIQYAIT EGRKSVTLVH KGNIMKFTEG AFKNWGYEVA 

       250        260        270        280        290        300 
EREFGDKVFT WAQYDKIVEE QGKEAADKAQ AEAEAAGKII VKDSIADIFL QQILTRPKEF 

       310        320        330        340        350        360 
DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYDTGHAI FEATHGTAPK YAGLDKVNPS 

       370        380        390        400        410        420 
SVLLSGELML RHLGWNEAAD LIMASMDKTI ESKVVTYDFA RLMDGATEVK CSEFANELIK 


NL 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB06878.1.
PIRG84044.
RefSeqNP_244025.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K848.
SMRQ9K848. Positions 1-422.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH3159.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB06878; BAB06878; BAB06878.
GeneID890641.
KEGGbha:BH3159.
PATRIC18943574. VBIBacHal18977_3286.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-3258-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9K848_BACHD
AccessionPrimary (citable) accession number: Q9K848
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 13, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)