Reviewed, UniProtKB/Swiss-Prot Q9K815 (ACKA_BACHD)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BH3192

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 391	391	Acetate kinase HAMAP MF_00020		PRO_0000107530

Sequences

	Sequence		Length	Mass (Da)
	Q9K815-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: A9EC525BADFC6275	FASTA	391	42,766
	10 20 30 40 50 60 MAINAGSSSL KFQLLNMPEE ELVTKGVVER IGLGDGIFTI EVKGEKVTET FDIPDHAFAV 70 80 90 100 110 120 KTLLEKLTSH EIIQSLDEIE GIGHRVVHGG EKFNDSVLIT DEVIQGIEEC NELAPLHNPA 130 140 150 160 170 180 NIVGIRAFKE VLPNVPAVAV FDTAFHQTMP ESSFLYSLPY DYYKEFGIRK YGFHGTSHKY 190 200 210 220 230 240 VSQRAAELLG RPIEQLRLLS CHLGNGASIA AIDGGKSIDT SMGFTPLAGV TMGTRSGNID 250 260 270 280 290 300 PALIPFIMEK TGQTANEVIN TLNKKSGLLG VSGFSSDLRD IEEQAGEGND RAELALEVFT 310 320 330 340 350 360 SRIHKYIGSY AARMSGVDAI IFTAGIGENS TVIRERVLRG LEFMGVYWDP SLNQVRGKEA 370 380 390 FINYPHSPVK VLVIPTNEEV MIARDTVRLA Q

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000004 Genomic DNA. Translation: BAB06911.1.
PIR	H84048.
RefSeq	NP_244058.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	890818.
GenomeReviews	Gene locus BH3192 in contig BA000004_GR.
KEGG	bha:BH3192.
NMPDR	fig|272558.1.peg.3192.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9K815.
OMA	SSDFRDV.
Enzyme and pathway databases
BioCyc	BHAL272558:BH3192-MON.
BRENDA	2.7.2.1. 191865.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. False negative. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BACHD

Accession

Primary (citable) accession number: Q9K815

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)