Q9K6J4 (FABZ_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	BH3735

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	140 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 140	140	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000091638
Sites
	Active site	48	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9K6J4 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: CD9A9E629077A9A4	FASTA	140	15,525
	10 20 30 40 50 60 MLTIEDIKKI IPHRYPFLLI DRLEELEDGK RAVGIKNVTV NEDFFNGHFP DYPVMPGVLI 70 80 90 100 110 120 VEALAQVGAC AILNVEENKG KLAFFAGIDN CRFKEQVKPG DQLRLEVEIV RMKGPVGKGR 130 140 GVASVNGKTV AETDLMFAIK

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB07454.1.
PIR	G84116.
RefSeq	NP_244602.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9K6J4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050302; EBBACP00000048941; EBBACG00000050293.
GeneID	890929.
GenomeReviews	Gene locus BH3735 in contig BA000004_GR.
KEGG	bha:BH3735.
NMPDR	fig|272558.1.peg.3735.
PATRIC	18944778. VBIBacHal18977_3887.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002061.
HOGENOM	HBG433282.
OMA	KKQVTPG.
PhylomeDB	Q9K6J4.
Enzyme and pathway databases
BioCyc	BHAL272558:BH3735-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_BACHD

Accession

Primary (citable) accession number: Q9K6J4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2001
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program