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Q9K6B9 (SPEB_BACHD) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Agmatinase

EC=3.5.3.11
Alternative name(s):
Agmatine ureohydrolase
Short name=AUH
Gene names
Name:speB
Ordered Locus Names:BH3810
OrganismBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]
Taxonomic identifier272558 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of putrescine from agmatine By similarity.

Catalytic activity

Agmatine + H2O = putrescine + urea.

Cofactor

Manganese By similarity.

Pathway

Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1.

Sequence similarities

Belongs to the arginase family. Agmatinase subfamily.

Sequence caution

The sequence BAB07529.1 differs from that shown. Reason: Frameshift at position 40.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 289289Agmatinase
PRO_0000173727

Sites

Metal binding1121Manganese By similarity
Metal binding1351Manganese By similarity
Metal binding1371Manganese By similarity
Metal binding1391Manganese By similarity
Metal binding2161Manganese By similarity
Metal binding2181Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9K6B9 [UniParc].

Last modified March 15, 2004. Version 2.
Checksum: 2F8B0C4CA4EB4B89

FASTA28932,155
        10         20         30         40         50         60 
MRFDEAYSGK VFIMSRSNYE KSKAVIFGMP MDWTVSFRPS SRFGPNRIRE ASLGLEEYSP 

        70         80         90        100        110        120 
YMDKHLEEVA YFDAGDMLLP FGNPQRSLEM IESYVDKLLA DQKMPIGLGG EHLVSWPIFK 

       130        140        150        160        170        180 
AMHKIYPDMA IIHIDAHADL REEYEGEPLS HSTPIRKACS LIGPENVYSF GIRSGMREEF 

       190        200        210        220        230        240 
QYAKDSGMYM AKFEVATPLK EVLPKLAGRN VYVTIDIDVL DPAFAPGTGT AEAGGISSKE 

       250        260        270        280 
LLEAIVAIAH SDVNVIGADL VEVAPAYDPS EKTPIAASKF VREMLLGWV 

« Hide

References

[1]"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000004 Genomic DNA. Translation: BAB07529.1. Frameshift.
PIRB84126.
RefSeqNP_244677.1. NC_002570.2.

3D structure databases

ProteinModelPortalQ9K6B9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272558.BH3810.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB07529; BAB07529; BAB07529.
GeneID890481.
KEGGbha:BH3810.
PATRIC18944936. VBIBacHal18977_3966.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0010.
KOK01480.
OMAEMPRFAG.

Enzyme and pathway databases

BioCycBHAL272558:GJC5-3913-MONOMER.
UniPathwayUPA00534; UER00287.

Family and domain databases

Gene3D3.40.800.10. 1 hit.
InterProIPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERPTHR11358. PTHR11358. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
TIGRFAMsTIGR01230. agmatinase. 1 hit.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEB_BACHD
AccessionPrimary (citable) accession number: Q9K6B9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: March 15, 2004
Last modified: October 16, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways