ID   Q9K629_HALH5            Unreviewed;       695 AA.
AC   Q9K629;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 115.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAB07622.1};
GN   Name=mcpB {ECO:0000313|EMBL:BAB07622.1};
OS   Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC   Halalkalibacterium (ex Joshi et al. 2022).
OX   NCBI_TaxID=272558 {ECO:0000313|EMBL:BAB07622.1, ECO:0000313|Proteomes:UP000001258};
RN   [1] {ECO:0000313|EMBL:BAB07622.1, ECO:0000313|Proteomes:UP000001258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125
RC   {ECO:0000313|Proteomes:UP000001258};
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BA000004; BAB07622.1; -; Genomic_DNA.
DR   PIR; G84137; G84137.
DR   RefSeq; WP_010900028.1; NC_002570.2.
DR   AlphaFoldDB; Q9K629; -.
DR   STRING; 272558.gene:10729816; -.
DR   KEGG; bha:BH3903; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 9762005at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001258};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        311..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          335..390
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          409..666
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   695 AA;  75712 MW;  2470FCA8AC64F44F CRC64;
     MTLRTKMLVL ILGSVFIIFG AVSAYSMYKT NQISVHMTSE LMESENDRLA LEVQLEVELA
     LDSARALAHG LQGLKENDTA SRDEVNAMLT AVLRENPTFI GTWTIWEPDA FDGKDEEFAG
     TDLHDATGRY IPYFYRGDNG QVLSEPSRDY DVPGDGDYYL VPKEAGKEVV LEPYLYEMNG
     ELIMFLSVAV PVIDSGETVG VVGIDLSLDY IQDFINDYTF FDTGYGLLIS NEGQVVSHPQ
     AENVGGDIST LLPASMVQRV MERLKQGEDA SFTVDSLIYD MSPVRLGQTD TPWSVMVIVP
     QKEVMAESRH LLFLLIGAVS AGLILITIII VLIANNIIKP IKATIDVGNH LAQGDFTKDI
     PEAYLQRPDE VGDIARSFNS MKQSLSAMIH NVLKHAEQAA AASQELATSA EETKQTSNQI
     AVTINEIAEG ATGQSEHAAS ILERMKTTVL EAQKGQQASI HALELANQSN QSALKGEQVT
     RTTVEHLQEV NAQVRTSVES VKSLGERSEE IGSIVTDISS IADQTNLLAL NAAIEAARAG
     EHGKGFAVVA EEVRKLAAQS AESADKITQL VGGIQGETKE IVQLIEQNLV SVQRQMEYIQ
     EVGRSLREIV HHTEGTKEQS QDMNSVLTQV LNHAETVLSS IEEISSIIEQ SAASAEEVAA
     GAEEQSATVE EITNSSTNLA HMAEELNEEV SKFKL
//