Q9K5W7 (TGL_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-glutamine gamma-glutamyltransferase
EC=2.3.2.13

Alternative name(s):
Transglutaminase
Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BH3970

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus halodurans

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP-Rule MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP-Rule MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: HAMAP
Molecular_function	protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	Protein-glutamine gamma-glutamyltransferase HAMAP-Rule MF_00727		PRO_0000213724

Sequences

	Sequence		Length	Mass (Da)
	Q9K5W7 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 5A5A855E9B064F35	FASTA	284	32,578
	10 20 30 40 50 60 MGNDMIQVAG RPFSLESTTD FGRVERAILQ QMLDSSEWFS YSSMNELRFE LNVRINIMES 70 80 90 100 110 120 AKEMNASQVT FTIFEHASCN PEYWTLTSTG GFLVRSDVRP SDAILDIYRN GTLYGFECAT 130 140 150 160 170 180 AIIIIYYQAI LKSIGQLRFD SIFQHLYLYS WHTHPGLELH TFHADRFLPG DVVYFNNPDF 190 200 210 220 230 240 HPDTPWFRGE NAVVLSDGTF FGHGFGIMTA EQMIQSLNSY RFPGSMQPAY LANLITRISP 250 260 270 280 LTIRNLLTLQ SDRTTYHYSK AVIHHNLCSI SSMDYQYYLL SLNG

References

[1]

"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB07689.1.
PIR	B84146.
RefSeq	NP_244838.1. NC_002570.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	272558.BH3970.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB07689; BAB07689; BAB07689.
GeneID	892624.
KEGG	bha:BH3970.
PATRIC	18945268. VBIBacHal18977_4132.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG12337.
HOGENOM	HOG000262157.
KO	K00686.
OMA	FECATAI.
ProtClustDB	PRK03187.
Enzyme and pathway databases
BioCyc	BHAL272558:GJC5-4073-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl.
InterPro	IPR020916. Gln_gamma-glutamylTfrase_bac. [Graphical view]
ProDom	PD119415. PD119415. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

TGL_BACHD

Accession

Primary (citable) accession number: Q9K5W7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program