ID   Q9K465_STRCO            Unreviewed;       667 AA.
AC   Q9K465;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   RecName: Full=PPM-type phosphatase domain-containing protein {ECO:0000259|SMART:SM00331};
GN   OrderedLocusNames=SCO7220 {ECO:0000313|EMBL:CAB94643.1};
GN   ORFNames=SC2H12.19c {ECO:0000313|EMBL:CAB94643.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB94643.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB94643.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939130; CAB94643.1; -; Genomic_DNA.
DR   RefSeq; NP_631276.1; NC_003888.3.
DR   AlphaFoldDB; Q9K465; -.
DR   STRING; 100226.gene:17764880; -.
DR   PaxDb; 100226-SCO7220; -.
DR   PATRIC; fig|100226.15.peg.7319; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   InParanoid; Q9K465; -.
DR   OrthoDB; 118142at2; -.
DR   PhylomeDB; Q9K465; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT   DOMAIN          314..539
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   667 AA;  71208 MW;  CF1A4DE51D82F7ED CRC64;
     MGRQEQILGA VNLDRELRVT HRNLEAPVFA GLDAAVGSPF VDLLPPGDVP TVTRRLRQVL
     DTGEAHVARV QRLRRGDGSE LVVSMSILPA AAPREGLTVS VIAMARRLHL YAAETAIGTS
     LDIGETAQSL AESLLAWGDV AAVDLDFAVW TGEGVTERAQ GRIRLRRAAL VPDRAWPEGY
     VTLGEDLPSD ASRLLSQAIR RADAPQSIVI PDREAIERVL GSPRLVRALV PGDRSAGVAC
     VPLVLEGDPP VVLGVAEVWR RADRPFADSE LFDLQELVAR TSHHVDLARQ HQREHTQVLA
     LQRRLLPRSA GGTVQTASVY QPATPDSAGV GGDWVNSFPL PDGRTALVVG DVVGHGLGAA
     ATMGQLSMEA RALLSAGLAP DEVLEHLDET VTLLDDAESG LAAGYSALGS TCCIAVYDPV
     SHRVTLSSAG HLPPILVSPD GRAGPLPVRP HPGLGTEFAL REPYGVHTFV APPGSLLALY
     TDGLVEDPAV PIDEGIARLA DAVSGVHPWD SLQQAARRVV SDVMPAHQRD DVTLLIARTI
     GYRKGDTATW RLPARDDAAA RARALVSALL RQWRTRDSTR DSVLLLVSEL VTNAVRFAGG
     PITVRLIRAG PGLLCEVGDT GNGRPRLGRG GLLDDGGRGL HVVHRLTTRW GVRWTDTGKV
     VWAEVVR
//