ID   Q9K406_STRCO            Unreviewed;       387 AA.
AC   Q9K406;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAB95784.1};
GN   OrderedLocusNames=SCO1327 {ECO:0000313|EMBL:CAB95784.1};
GN   ORFNames=2SCG61.09 {ECO:0000313|EMBL:CAB95784.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB95784.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB95784.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939108; CAB95784.1; -; Genomic_DNA.
DR   RefSeq; NP_625612.1; NC_003888.3.
DR   AlphaFoldDB; Q9K406; -.
DR   STRING; 100226.gene:17758910; -.
DR   PaxDb; 100226-SCO1327; -.
DR   PATRIC; fig|100226.15.peg.1331; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_1_1_11; -.
DR   InParanoid; Q9K406; -.
DR   OrthoDB; 3210173at2; -.
DR   PhylomeDB; Q9K406; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        68..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          146..386
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
FT   REGION          224..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  41990 MW;  59B10B2A26BE5273 CRC64;
     MGVGRAAAEY RRKAEQHPWP PRWLRWLPPS LILVTMALDH ATPPRYFFGS LLTASVVLAI
     FVYRPLGVAA TGAIGCLFLA VTVQIEDYIG PMTVVALVVL GSVTLLSVVL CVMLQRAASR
     YRRVLAVAEA AQLALLRPLP DRIGSLRMAG FYRAADDEAL IGGDLYSVRP TPFGVRAIVG
     DVKGKGINAT QTVATVISTF QEAALLHPTL PQVADRIDVA LQLDRDNPPP EPVSHTQPEH
     GADDAKGLVD ELFTTAVLLE FTSDARTVQV LDRGHQPLLI VRRHTTSVVP AEHSLPLGMA
     DLLTEPPGTT ACRLEPGDIL LAYSDGVTEA RDSTGTFYPL PERLQHHYAT SAQPVSPSDL
     ISFLQEDVTR WAHTLGDDVI AIAFQRI
//