ID   Q9K3K0_STRCO            Unreviewed;       712 AA.
AC   Q9K3K0;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 124.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:CAB97423.1};
GN   OrderedLocusNames=SCO4820 {ECO:0000313|EMBL:CAB97423.1};
GN   ORFNames=SC2A6.05c {ECO:0000313|EMBL:CAB97423.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB97423.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAB97423.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939121; CAB97423.1; -; Genomic_DNA.
DR   RefSeq; NP_628976.1; NC_003888.3.
DR   RefSeq; WP_011029888.1; NZ_VNID01000016.1.
DR   AlphaFoldDB; Q9K3K0; -.
DR   STRING; 100226.gene:17762469; -.
DR   CAZy; GH23; Glycoside Hydrolase Family 23.
DR   PaxDb; 100226-SCO4820; -.
DR   PATRIC; fig|100226.15.peg.4897; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG0741; Bacteria.
DR   HOGENOM; CLU_024190_0_0_11; -.
DR   InParanoid; Q9K3K0; -.
DR   OrthoDB; 9801841at2; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00254; LT-like; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR44329:SF214; ANKYRIN REPEAT-CONTAINING PROTEIN KINASE A-RELATED; 1.
DR   PANTHER; PTHR44329; SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000313|EMBL:CAB97423.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:CAB97423.1};
KW   Transferase {ECO:0000313|EMBL:CAB97423.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        408..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        507..526
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          218..486
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          27..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   712 AA;  74552 MW;  F116E60BEBDC8694 CRC64;
     MTEPYAVPVP RGYRVGVWEV HAPIATGAFG SVYAARRTGG DDTKASPTRP GGDDNTKAPP
     TRPGGDGTGH RPSRPGTTDT AGTDDSHGTG TGTGTGTPSR AQTDTAHPAE GDTDDPGHTS
     GNGTTGTDGT RRSHGTGTGT PSRAHTDTAH PAEGDTDNPG HTSGNGTTGT DGTGRSHGTG
     TGTGTHNPSR VQTGAAHPAK GDTDNPGRTG GDGTARRPGR AGVVGAGRGG DAGGEVPDTV
     ALKFLPTGTG TPRQLAHLRD LVEREVELLR RLRRPRLIRM YETLTVDDPA HPRLDGATVL
     VLERAEGSLS ALLAATPRPP AGPALLAQVC EGLQQLHRAG WVHGDLKPAN VLLMADGSAR
     LADFNMAAEL EGTHAYTPAF ATPDYTPPEL LWSEIGERGR RIRPSADVWA FGVLAHLVLT
     GSFPLPGGTP TARRDAAVAY ARGGHELRLS PEPPPGWREI VRACLTRTHA DRIGTDALLR
     RVTGTTEGAS GGAGFSPRTR ARPRRRVLAA LAAGLLALAA LGYGVARWAG DGREPAAGPR
     PGGTGSVAAA SYGAAELRTD RDVPPAYRLL IVETAHDCDR EEVSPALIAA MLKVESDFDP
     DLADPAKDEY GIARWTPSVL RWWMNEDGTP GETVPQPPFP PAESVPAMGR YLCWIAPRLD
     AGLPGDRSVL VAVAYRTSYR KVNDAGGVPP KYRDYADRVA HHLKEYTPRR GK
//