Reviewed, UniProtKB/Swiss-Prot Q9K1H5 (DADA_NEIMB)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	NMB0176

Organism

Neisseria meningitidis serogroup B [Complete proteome] [HAMAP]

Taxonomic identifier

491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced acceptor.
Cofactor	FAD By similarity.
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	D-amino acid dehydrogenase small subunit		PRO_0000166136
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9K1H5-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: E50C13F9DFBC214D	FASTA	418	46,535
	10 20 30 40 50 60 MKVLVLGAGV AGVSSAWYLA EAGHEVTVID RAEGVAMETS FANAGQLSYG YTTPWAAPGI 70 80 90 100 110 120 PTKALKWLFK SHPPLLFRPD GSLYQIEWLW QMLQNCTAAH YQTNKERMVR ISEYSREMFR 130 140 150 160 170 180 RFEAQTGMNF EGRKKGTLQI FRQTKEVEAA KQDIAVLERY GVPYRRLKPE ECAEFEPALA 190 200 210 220 230 240 RVTAKIAGGL HLPADATGDC RLFTENLYKL CQEKGVRFHF NQNISRIDHN GLRIKTVETE 250 260 270 280 290 300 TGRFEADAVV CALGCFSRTV LAQLDLNLPI YPVKGYSLTL PVTNSDGAPV STVLDESYKV 310 320 330 340 350 360 AITRFDNRIR VGGMAELSGY EIKLPEKRRE TLALVVNDLF PEGGDLSQAS FWSGLRPMTP 370 380 390 400 410 DSTPLIGRTR FDNLFLNTGH GTLGWTMSLG SAKLTADIVS GKDTEIRSDD LSLSRYQA

References

[1]

"Complete genome sequence of Neisseria meningitidis serogroup B strain MC58." Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E., Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C., Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H., Salzberg S.L., White O. , Fleischmann R.D., Dougherty B.A., Mason T.M., Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D., Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V., Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M., Moxon E.R., Rappuoli R., Venter J.C. Science 287:1809-1815(2000) [PubMed: 10710307] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MC58 / Serogroup B.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE002098 Genomic DNA. Translation: AAF40633.1.
PIR	A81228.
RefSeq	NP_273234.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	902283.
GenomeReviews	Gene locus NMB0176 in contig AE002098_GR.
KEGG	nme:NMB0176.
NMPDR	fig|122586.1.peg.168.
TIGR	NMB0176.
Phylogenomic databases
HOGENOM	Q9K1H5.
Enzyme and pathway databases
BioCyc	NMEN122586:NMB_0176-MON.
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR000447. FAD-dep_Gly3P_DHase. IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
PRINTS	PR01001. FADG3PDH.
BLOCKS	Search...
ProtoNet	Search...

Entry information

Entry name

DADA_NEIMB

Accession

Primary (citable) accession number: Q9K1H5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	October 1, 2000
Last modified:	November 4, 2008
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)