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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 18FADUniRule annotation6
Nucleotide bindingi273 – 287NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processtRNA processing
LigandFAD, Flavoprotein, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:NMB0193
OrganismiNeisseria meningitidis serogroup B (strain MC58)
Taxonomic identifieri122586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001171411 – 628tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST628

Proteomic databases

PaxDbiQ9K1G0

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi122586.NMB0193

Structurei

3D structure databases

ProteinModelPortaliQ9K1G0
SMRiQ9K1G0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RE5 Bacteria
COG0445 LUCA
HOGENOMiHOG000201059
KOiK03495
OMAiFRPGYAI
OrthoDBiPOG091H01O0

Family and domain databases

Gene3Di3.50.50.602 hits
HAMAPiMF_00129 MnmG_GidA, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR026904 GidA-assoc_3
IPR004416 MnmG
IPR002218 MnmG-rel
IPR020595 MnmG-rel_CS
PANTHERiPTHR11806 PTHR11806, 1 hit
PTHR11806:SF0 PTHR11806:SF0, 1 hit
PfamiView protein in Pfam
PF01134 GIDA, 1 hit
PF13932 GIDA_assoc, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR00136 gidA, 1 hit
PROSITEiView protein in PROSITE
PS01280 GIDA_1, 1 hit
PS01281 GIDA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9K1G0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYPKTYDVI VVGGGHAGTE AALAAARMGA QTLLLSHNIE TLGQMSCNPS
60 70 80 90 100
IGGIGKGHLV RELDALGGAM ALATDKSGIQ FRRLNASKGA AVRATRAQAD
110 120 130 140 150
RILYKAAIRE MLENQENLDL FQQAVEDVTL DGERISGVIT AMGVEFKARA
160 170 180 190 200
VVLTAGTFLS GKIHIGLENY EGGRAGDPAA KSLGGRLREL KLPQGRLKTG
210 220 230 240 250
TPPRIDGRTI DFSQLTEQPG DTPVPVMSVR GNADMHPRQV SCWITHTNTQ
260 270 280 290 300
THDIIRSGFD RSPMFTGKIE GVGPRYCPSI EDKINRFADK DSHQIFLEPE
310 320 330 340 350
GLTTHEYYPN GISTSLPFDI QIALVRSMKG LENAHILRPG YAIEYDYFDP
360 370 380 390 400
RNLKASLETK TIAGLFFAGQ INGTTGYEEA AAQGLLAGAN AVQYVRGQDP
410 420 430 440 450
LLLRREQAYL GVLVDDLITK GVNEPYRMFT SRAEYRLQLR EDNADMRLTE
460 470 480 490 500
DGYKIGLVSE AQWRMFNEKR EAVEREIQRL KTTWYTPQKL AEGEQIRVFG
510 520 530 540 550
QKLSREANLH DLLRRPNLDY AALMTLEGAM PSENLSAEVI EQVEIQVKYQ
560 570 580 590 600
GYIDRQNEEI DSRRDIETLK LPDGIDYGKV KGLSAEVQQK LNQHKPETVG
610 620
QASRISGVTP AAVALLMVHL KRGFKDAK
Length:628
Mass (Da):69,438
Last modified:May 27, 2002 - v2
Checksum:i0265B68714660D6E
GO

Sequence cautioni

The sequence AAF40650 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA Translation: AAF40650.1 Different initiation.
PIRiF81227
RefSeqiNP_273251.1, NC_003112.2

Genome annotation databases

EnsemblBacteriaiAAF40650; AAF40650; NMB0193
GeneIDi902301
KEGGinme:NMB0193
PATRICifig|122586.8.peg.238

Similar proteinsi

Entry informationi

Entry nameiMNMG_NEIMB
AccessioniPrimary (citable) accession number: Q9K1G0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: May 27, 2002
Last modified: February 28, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome