Q9K0Y8 (Q9K0Y8_NEIMB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase EMBL AAF40854.1

Gene names

Name:	murF EMBL AAF40854.1
Ordered Locus Names:	NMB0416

Organism

Neisseria meningitidis serogroup B

Taxonomic identifier

491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL AAF40854.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Inferred from electronic annotation. Source: EC UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9K0Y8 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: E08BF767A558F7BB	FASTA	455	48,429
	10 20 30 40 50 60 MKPLDLNFIC QALKLPMPSE SKPVSRIVTD SRDIRAGDVF FALAGERFDA HDFVEDVLAA 70 80 90 100 110 120 GAAAVVVSRE DCAAMDGALK VDDTLAALQT LAKAWRENVN PFVFGITGSG GKTTVKEMLA 130 140 150 160 170 180 AVLRRRFGDD AVLATAGNFN NHIGLPLTLL KLNEKHRYAV IEMGMNHFGE LAVLTQIAKP 190 200 210 220 230 240 NAALVNNAMR AHVGCGFDGV GDIAKAKSEI YQGLCSDGIA LIPQEDANMA VFKTATLNLN 250 260 270 280 290 300 TRTFGIDSGD VHAENIVLKP LSCEFDLVCG DERAAVVLPV PGRHNVHNAA AAAALALAAG 310 320 330 340 350 360 LSLNDVAEGL KGFSNIKGRL NVKSGIKGAT LIDDTYNANP DSMKAAIDVL ARMPAPRIFV 370 380 390 400 410 420 MGDMGELGEL GEDEAAAMHA EVGAYARDQG IEAAYFVGDN SVEAAEKFGA DGLWFAAKDP 430 440 450 LIQVLRHDLP ERATVLVKGS RFMQMEEVVE ALEDK

References

[1]

"Complete genome sequence of Neisseria meningitidis serogroup B strain MC58." Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E., Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C., Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H., Salzberg S.L., White O. , Fleischmann R.D., Dougherty B.A., Mason T.M., Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D., Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V., Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M., Moxon E.R., Rappuoli R., Venter J.C. Science 287:1809-1815(2000) [PubMed: 10710307] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MC58 / Serogroup B.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE002098 Genomic DNA. Translation: AAF40854.1.
PIR	D81202.
RefSeq	NP_273464.1. NC_003112.2.
3D structure databases
HSSP	HSSP built from PDB template 1GG4 based on UniProtKB P11880.
ProteinModelPortal	Q9K0Y8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBNEIT00000009045; EBNEIP00000008665; EBNEIG00000009045.
GeneID	902532.
GenomeReviews	Gene locus NMB0416 in contig AE002098_GR.
KEGG	nme:NMB0416.
NMPDR	fig|122586.1.peg.398.
PATRIC	20356026. VBINeiMen85645_0528.
TIGR	NMB0416.
Phylogenomic databases
GeneTree	EBGT00050000020541.
HOGENOM	HBG617121.
OMA	YAVIEMG.
ProtClustDB	CLSK877543.
Family and domain databases
InterPro	IPR004101. Mur_ligase_C. IPR013221. Mur_ligase_cen. IPR000713. Mur_ligase_N. IPR005863. UDP-N-AcMur-pentapeptide_synth. [Graphical view]
Gene3D	G3DSA:3.90.190.20. Mur_ligase_C. 1 hit. G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit.
KO	K01929.
PANTHER	PTHR23135:SF3. MurF. 1 hit.
Pfam	PF01225. Mur_ligase. 1 hit. PF02875. Mur_ligase_C. 1 hit. PF08245. Mur_ligase_M. 1 hit. [Graphical view]
SUPFAM	SSF53244. Mur_ligase_C. 1 hit. SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMs	TIGR01143. MurF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9K0Y8_NEIMB

Accession

Primary (citable) accession number: Q9K0Y8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)