Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Na(+)-translocating NADH-quinone reductase subunit A

Gene

nqrA

Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.UniRule annotation

Catalytic activityi

NADH + ubiquinone + n Na+(In) = NAD+ + ubiquinol + n Na+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

NAD, Sodium, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
Na(+)-translocating NADH-quinone reductase subunit AUniRule annotation (EC:1.6.5.8UniRule annotation)
Short name:
Na(+)-NQR subunit AUniRule annotation
Short name:
Na(+)-translocating NQR subunit AUniRule annotation
Alternative name(s):
NQR complex subunit AUniRule annotation
NQR-1 subunit AUniRule annotation
Gene namesi
Name:nqrAUniRule annotation
Ordered Locus Names:NMB0569
OrganismiNeisseria meningitidis serogroup B (strain MC58)
Taxonomic identifieri122586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002142001 – 447Na(+)-translocating NADH-quinone reductase subunit AAdd BLAST447

Proteomic databases

PaxDbiQ9K0M3.

Interactioni

Subunit structurei

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.UniRule annotation

Protein-protein interaction databases

STRINGi122586.NMB0569.

Structurei

3D structure databases

ProteinModelPortaliQ9K0M3.
SMRiQ9K0M3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NqrA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWQ. Bacteria.
COG1726. LUCA.
HOGENOMiHOG000273652.
KOiK00346.
OMAiDYHGMKP.
OrthoDBiPOG091H03YP.

Family and domain databases

HAMAPiMF_00425. NqrA. 1 hit.
InterProiIPR008703. NqrA.
IPR022615. NqrA_C_domain.
[Graphical view]
PfamiPF05896. NQRA. 1 hit.
PF11973. NQRA_SLBB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01936. nqrA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9K0M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKIKKGLNL PIAGRPEQAV YDGPAITEVA LLGEEYAGMR PSMKVKEGDA
60 70 80 90 100
VKKGQVLFED KKNPGVVFTA PASGKIAAIH RGEKRVLQSV VIAVEGNDEI
110 120 130 140 150
EFERYAPEAL ANLSGEEVRR NLIQSGLWTA LRTRPFSKIP AVDAEPFAIF
160 170 180 190 200
VNAMDTNPLA ADPTVIIKEA AEDFKRGLLV LSRLTERKIH VCKAAGADVP
210 220 230 240 250
SENAANIETH EFGGPHPAGL SGTHIHFIEP VGANKTVWTI NYQDVITIGR
260 270 280 290 300
LFATGRLNTE RVIALGGSQV NKPRLLRTVL GAKVSQITAG ELVDTDNRVI
310 320 330 340 350
SGSVLNGAIT QGAHDYLGRY HNQISVIEEG RSKELFGWVA PQPDKYSITR
360 370 380 390 400
TTLGHFLKNK LFKFNTAVNG GDRAMVPIGT YERVMPLDIL PTLLLRDLIV
410 420 430 440
GDTDSAQALG CLELDEEDLA LCSFVCPGKY EYGPLLRKVL ETIEKEG
Length:447
Mass (Da):48,636
Last modified:October 1, 2000 - v1
Checksum:iBE174A78439BE477
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA. Translation: AAF40997.1.
PIRiD81185.
RefSeqiNP_273613.1. NC_003112.2.
WP_002225561.1. NC_003112.2.

Genome annotation databases

EnsemblBacteriaiAAF40997; AAF40997; NMB0569.
GeneIDi902684.
KEGGinme:NMB0569.
PATRICi20356417. VBINeiMen85645_0728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA. Translation: AAF40997.1.
PIRiD81185.
RefSeqiNP_273613.1. NC_003112.2.
WP_002225561.1. NC_003112.2.

3D structure databases

ProteinModelPortaliQ9K0M3.
SMRiQ9K0M3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi122586.NMB0569.

Proteomic databases

PaxDbiQ9K0M3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF40997; AAF40997; NMB0569.
GeneIDi902684.
KEGGinme:NMB0569.
PATRICi20356417. VBINeiMen85645_0728.

Phylogenomic databases

eggNOGiENOG4105DWQ. Bacteria.
COG1726. LUCA.
HOGENOMiHOG000273652.
KOiK00346.
OMAiDYHGMKP.
OrthoDBiPOG091H03YP.

Family and domain databases

HAMAPiMF_00425. NqrA. 1 hit.
InterProiIPR008703. NqrA.
IPR022615. NqrA_C_domain.
[Graphical view]
PfamiPF05896. NQRA. 1 hit.
PF11973. NQRA_SLBB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01936. nqrA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNQRA_NEIMB
AccessioniPrimary (citable) accession number: Q9K0M3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.