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Protein

Outer membrane protein assembly factor BamD

Gene

bamD

Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Required for efficient transformation of Neisseria meningitidis by species-related DNA.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Competence

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein assembly factor BamDUniRule annotation
Alternative name(s):
Competence lipoprotein ComL
Gene namesi
Name:bamDUniRule annotation
Synonyms:comL
Ordered Locus Names:NMB0703
OrganismiNeisseria meningitidis serogroup B (strain MC58)
Taxonomic identifieri122586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000425 Componenti: Chromosome

Subcellular locationi

  • Cell outer membrane UniRule annotation; Lipid-anchor UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16UniRule annotationAdd BLAST16
ChainiPRO_000003622317 – 267Outer membrane protein assembly factor BamDAdd BLAST251

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi17N-palmitoyl cysteineUniRule annotation1
Lipidationi17S-diacylglycerol cysteineUniRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ9K0B1.
PRIDEiQ9K0B1.

Interactioni

Subunit structurei

Part of the Bam complex.UniRule annotation

Protein-protein interaction databases

STRINGi122586.NMB0703.

Family & Domainsi

Sequence similaritiesi

Belongs to the BamD family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106SNF. Bacteria.
COG4105. LUCA.
HOGENOMiHOG000260923.
KOiK05807.
OMAiIHVADYY.
OrthoDBiPOG091H048Z.

Family and domain databases

CDDicd15830. BamD. 1 hit.
Gene3Di1.25.40.10. 1 hit.
HAMAPiMF_00922. OM_assembly_BamD. 1 hit.
InterProiIPR017689. BamD.
IPR011990. TPR-like_helical_dom.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
TIGRFAMsiTIGR03302. OM_YfiO. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9K0B1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKILLTVSL GLALSACATQ GTVDKDAQIT QDWSVEKLYA EAQDELNSSN
60 70 80 90 100
YTRAVKLYEI LESRFPTSRH AQQSQLDTAY AYYKDDEKDK ALAAIDRFRR
110 120 130 140 150
LHPQHPNMDY ALYLRGLVLF NEDQSFLNKL ASQDWSDRDP KANREAYQAF
160 170 180 190 200
AELVQRFPNS KYAADATARM VKLVDALGGN EMSVARYYMK RGAYIAAANR
210 220 230 240 250
AQKIIGSYQN TRYVEESLAI LELAYKKLDK PRLAADTRRV LETNFPKSPF
260
LKQPWRSDDM PWWRYWH
Length:267
Mass (Da):30,915
Last modified:October 1, 2000 - v1
Checksum:i26B4588A67A7E223
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA. Translation: AAF41120.1.
PIRiH81167.
RefSeqiNP_273745.1. NC_003112.2.
WP_002244053.1. NC_003112.2.

Genome annotation databases

EnsemblBacteriaiAAF41120; AAF41120; NMB0703.
GeneIDi902815.
KEGGinme:NMB0703.
PATRICi20356747. VBINeiMen85645_0895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA. Translation: AAF41120.1.
PIRiH81167.
RefSeqiNP_273745.1. NC_003112.2.
WP_002244053.1. NC_003112.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi122586.NMB0703.

Proteomic databases

PaxDbiQ9K0B1.
PRIDEiQ9K0B1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF41120; AAF41120; NMB0703.
GeneIDi902815.
KEGGinme:NMB0703.
PATRICi20356747. VBINeiMen85645_0895.

Phylogenomic databases

eggNOGiENOG4106SNF. Bacteria.
COG4105. LUCA.
HOGENOMiHOG000260923.
KOiK05807.
OMAiIHVADYY.
OrthoDBiPOG091H048Z.

Family and domain databases

CDDicd15830. BamD. 1 hit.
Gene3Di1.25.40.10. 1 hit.
HAMAPiMF_00922. OM_assembly_BamD. 1 hit.
InterProiIPR017689. BamD.
IPR011990. TPR-like_helical_dom.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
TIGRFAMsiTIGR03302. OM_YfiO. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBAMD_NEIMB
AccessioniPrimary (citable) accession number: Q9K0B1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Present in outer membrane vesicle formulations which are used as vaccines in human.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.