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Q9JZP4 (SUCC_NEIMB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit beta
EC=6.2.1.5
Alternative name(s):
Succinyl-CoA synthetase subunit beta
Short name=SCS-beta
Gene names
Name:sucC
Ordered Locus Names:NMB0959
OrganismNeisseria meningitidis serogroup B
Taxonomic identifier491 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP MF_00558

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. HAMAP MF_00558

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Contains 1 ATP-grasp domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 388388Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP MF_00558
PRO_0000102842

Regions

Domain9 – 245237ATP-grasp
Nucleotide binding35 – 10975ATP By similarity

Sites

Metal binding1981Magnesium or manganese By similarity
Metal binding2001Magnesium or manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9JZP4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 361E70FBF49ADEF9

FASTA38841,336
        10         20         30         40         50         60 
MNLHEYQAKE LLASYGLPVQ GGILAHNGEE AAAAYDKLGG KFAVVKAQVH AGGRGKAGGV 

        70         80         90        100        110        120 
KVVKSREEAK EVAESLIGTN LVTYQTDANG QPVNSVLVCE DMYPVQTELY LGAVVDRSTR 

       130        140        150        160        170        180 
RITFMASTEG GVEIEKVAAE TPEKIFKVTV DPLVGLQPCQ AREVAFQLGL KDKQINEFVK 

       190        200        210        220        230        240 
LMTGAYKAFV ENDFALFEVN PLAVRENGAL ACVDGKIGID SNALYRLPKI AELRDKSQEN 

       250        260        270        280        290        300 
ERELKASEFD LNYVALEGNI GCMVNGAGLA MATMDIIKLK GGQPANFLDV GGGATKDRVV 

       310        320        330        340        350        360 
EAFKLILEDK SVQGVLINIF GGIVRCDMIA EAIVAAVKEI NVNVPVVVRL EGNNAELGAK 

       370        380 
ILNESGLKLT SADGLNDAAE KIVAAVNA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE002098 Genomic DNA. Translation: AAF41365.1.
PIRF81137.
RefSeqNP_273997.1. NC_003112.2.

3D structure databases

ProteinModelPortalQ9JZP4.
SMRQ9JZP4. Positions 1-386.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBNEIT00000009797; EBNEIP00000009417; EBNEIG00000009797.
GeneID903079.
GenomeReviewsGene locus NMB0959 in contig AE002098_GR.
KEGGnme:NMB0959.
NMPDRfig|122586.1.peg.931.
PATRIC20357399. VBINeiMen85645_1214.
TIGRNMB0959.

Phylogenomic databases

GeneTreeEBGT00050000021023.
HOGENOMHBG315432.
OMAIGGDMWV.
ProtClustDBPRK00696.

Enzyme and pathway databases

BioCycNMEN122586:NMB_0959-MONOMER.

Family and domain databases

HAMAPMF_00558. Succ_CoA_beta.
[Tree]
InterProIPR011761. ATP-grasp.
IPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005811. CoA_ligase.
IPR017866. Succ-CoA_synthase_bsu_CS.
IPR005809. Succ_CoA_synthase_bsu.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
Gene3DG3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit.
G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
G3DSA:3.40.50.261. Succinyl-CoA_synth-like. 1 hit.
KOK01903.
PANTHERPTHR11815. CoA_lig_beta. 1 hit.
PfamPF08442. ATP-grasp_2. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001554. SucCS_beta. 1 hit.
SUPFAMSSF52210. CoA_ligase. 1 hit.
TIGRFAMsTIGR01016. SucCoAbeta. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS01217. SUCCINYL_COA_LIG_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUCC_NEIMB
AccessionPrimary (citable) accession number: Q9JZP4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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