Reviewed, UniProtKB/Swiss-Prot Q9JZB4 (GLND_NEIMB)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	NMB1203

Organism

Neisseria meningitidis serogroup B [Complete proteome] [HAMAP]

Taxonomic identifier

491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	852 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 852	852	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192748

Sequences

	Sequence		Length	Mass (Da)
	Q9JZB4-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 1F377E3C95355F1B	FASTA	852	97,008
	10 20 30 40 50 60 MPANLSSALE TFKQQRDAAE AHYLKANRVS VFFREYTAAV ETLLAALWAE YFQNSALCLM 70 80 90 100 110 120 AVGGFGRGEL YPCSDVDLAV VSPAPLSDGI QEQIARFVQT LWDCKLMPSV KSGSVDELCE 130 140 150 160 170 180 SVRNDITGDT AFLEARFLFG NRQTVDKLAE KMNAQRNVAA FVEAKLVEME HRHAKSQGSG 190 200 210 220 230 240 AVLEPNIKSC PGGLRDIHTL LWIAKAQGLA TDLPDLLKQR ILTRAEAGML SHGYRRLAHI 250 260 270 280 290 300 RIHLHLNAKR AEDRLLFDLQ PQVAESMGYE GLNLRRQSEE LMRVFYRAIK TVKQLGGILT 310 320 330 340 350 360 PMLQSRVSST PLRVTLRIDD DYIQVNNQIA ARHTDIFFRR PEHIFKIVEI MQQRNDITAL 370 380 390 400 410 420 EPQTLRAWWG ATRKINRSFY QNPENRRRFA GFFRNGNGLT QTLRFLNLYG VLGRYLPAWE 430 440 450 460 470 480 KIIGLLQHDL FHIYPVDDHI LTVVRNVRRL ALDMHSHELP YASALMQSFE KQDILYLAAF 490 500 510 520 530 540 FHDIAKGRGG DHAIQGIADA RQFAADHFLT GEESDLLAWL VENHLLMSAV AQKEDIQDPS 550 560 570 580 590 600 VLDAFCKRVQ THERLSALYL LTISDIRGTN PKLWNAWRAS LLESLFHAAG RYLTGNGGNP 610 620 630 640 650 660 HTLFGRRRQE AADLLTRAAV PEKQQKKLWN ALGSAYFARH QSREILWHAA NLVHDFETPI 670 680 690 700 710 720 VRSRILPKSD SFQVMVFMPN GPRLFARLCR IFSRHGFDIL AARAFITEHD YILDTFIVQI 730 740 750 760 770 780 PSQHAPEDYP DIQSALEAEL NSFIHGHTVA ETQSRSRRIS RRSRYMPIAP SITITPEEDY 790 800 810 820 830 840 PDWYSVEITA VNRPFLLADM AEVFFAHNVS LRYAKISTLD ERAEDSFTVF SPDLKNPKIQ 850 SSLKQTLLEQ LS

References

[1]

"Complete genome sequence of Neisseria meningitidis serogroup B strain MC58." Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E., Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C., Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H., Salzberg S.L., White O. , Fleischmann R.D., Dougherty B.A., Mason T.M., Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D., Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V., Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M., Moxon E.R., Rappuoli R., Venter J.C. Science 287:1809-1815(2000) [PubMed: 10710307] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MC58 / Serogroup B.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE002098 Genomic DNA. Translation: AAF41585.1.
PIR	B81110.
RefSeq	NP_274228.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	903625.
GenomeReviews	Gene locus NMB1203 in contig AE002098_GR.
KEGG	nme:NMB1203.
NMPDR	fig|122586.1.peg.1162.
TIGR	NMB1203.
Phylogenomic databases
HOGENOM	Q9JZB4.
OMA	MQHDLFH.
Enzyme and pathway databases
BioCyc	NMEN122586:NMB_1203-MON.
BRENDA	2.7.7.59. 293828.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR005105. DUF294_Ntrans. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF03445. DUF294. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NEIMB

Accession

Primary (citable) accession number: Q9JZB4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 8, 2000
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)