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Protein

S-formylglutathione hydrolase

Gene

NMB1305

Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Serine hydrolase involved in the detoxification of formaldehyde.UniRule annotation

Catalytic activityi

S-formylglutathione + H2O = glutathione + formate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Serine esteraseUniRule annotation

Protein family/group databases

ESTHERineime-ESD. A85-EsteraseD-FGH.
MEROPSiS09.A38.

Names & Taxonomyi

Protein namesi
Recommended name:
S-formylglutathione hydrolaseUniRule annotation (EC:3.1.2.12UniRule annotation)
Gene namesi
Ordered Locus Names:NMB1305Imported
OrganismiNeisseria meningitidis serogroup B (strain MC58)Imported
Taxonomic identifieri122586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000425 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiQ9JZ43.

Interactioni

Protein-protein interaction databases

STRINGi122586.NMB1305.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4B6GX-ray1.40A/B3-275[»]
ProteinModelPortaliQ9JZ43.
SMRiQ9JZ43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the esterase D family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C4W. Bacteria.
COG0627. LUCA.
HOGENOMiHOG000263929.
KOiK01070.
OMAiEDHLRHH.
OrthoDBiPOG091H0560.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR000801. Esterase_put.
IPR014186. S-formylglutathione_hydrol.
PANTHERiPTHR10061. PTHR10061. 1 hit.
PfamiView protein in Pfam
PF00756. Esterase. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR02821. fghA_ester_D. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9JZ43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIEQHQIF GGSQQVWAHH AQTLQCEMKF AVYLPNNPEN RPLGVIYWLS
60 70 80 90 100
GLTCTEQNFI TKSGFQRYAA EHQVIVVAPD TSPRGEQVPN DDAYDLGQSA
110 120 130 140 150
GFYLNATEQP WAANYQMYDY ILNELPRLIE KHFPTNGKRS IMGHSMGGHG
160 170 180 190 200
ALVLALRNQE RYQSVSAFSP ILSPSLVPWG EKAFTAYLGK DREKWQQYDA
210 220 230 240 250
NSLIQQGYKV QGMRIDQGLE DEFLPTQLRT EDFIETCRAA NQPVDVRFHK
260 270
GYDHSYYFIA SFIGEHIAYH AAFLK
Length:275
Mass (Da):31,431
Last modified:October 1, 2000 - v1
Checksum:i5D3AE8477A35775E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002098 Genomic DNA. Translation: AAF41680.1.
PIRiG81097.
RefSeqiNP_274324.1. NC_003112.2.
WP_002225169.1. NC_003112.2.

Genome annotation databases

EnsemblBacteriaiAAF41680; AAF41680; NMB1305.
GeneIDi903727.
KEGGinme:NMB1305.
PATRICifig|122586.8.peg.1637.

Similar proteinsi

Entry informationi

Entry nameiQ9JZ43_NEIMB
AccessioniPrimary (citable) accession number: Q9JZ43
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: August 30, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported