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Q9JYX3

- G6PI1_NEIMB

UniProt

Q9JYX3 - G6PI1_NEIMB

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Protein

Glucose-6-phosphate isomerase 1

Gene

pgi1

Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei353 – 3531Proton donorBy similarity
Active sitei384 – 3841By similarity
Active sitei512 – 5121By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciNMEN122586:GHGG-1426-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
Short name:
GPI 1
Alternative name(s):
Phosphoglucose isomerase 1
Short name:
PGI 1
Phosphohexose isomerase 1
Short name:
PHI 1
Gene namesi
Name:pgi1
Ordered Locus Names:NMB1388
OrganismiNeisseria meningitidis serogroup B (strain MC58)
Taxonomic identifieri122586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000000425: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomerase 1PRO_0000180693Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi122586.NMB1388.

Structurei

3D structure databases

ProteinModelPortaliQ9JYX3.
SMRiQ9JYX3. Positions 3-545.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9JYX3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKHLHDLPAW SKLWNHFDDS KTLHMREMFE QDPQRAERYW LQVGGLTLDY
60 70 80 90 100
SKNRINDETM SLLFELAREA GVPERMRQMF HGEKINTTEN RAVLHVALRN
110 120 130 140 150
RTNSPIVVDG EDVMPKVNRV LQRMGEFAHE VRSGSWLGYT NQVITDVVNI
160 170 180 190 200
GIGGSDLGPL MMCTALKPFG HPRLNMHFVS NVDGSQLRDV LSKVHPETTL
210 220 230 240 250
FIIASKTFTT QETLTNALTA REWFLNHAGD EEAVAKHFAA VSTNQKAVAE
260 270 280 290 300
FGIDTANMFE FWDWVGGRYS LWSAIGLPIM LYLGEENFIE MLNGAHLMDQ
310 320 330 340 350
HFINTPLERN LPVILALIGI WYINYYGGGS HVIAPYDQHL HRLPKFIQQL
360 370 380 390 400
DMESNGKQVT LDGKAVGHET SPIIWGETGI NGQHAFFQLL HQGTHITPID
410 420 430 440 450
LIASLEKRSN LPGHHEILLA NVFAQAEAFM RGKTPDEVRA ELKAQGMDEV
460 470 480 490 500
RIEELVPHKT FSGNRPTNLI LMDKVNPRNM GSLIAMYEHK TFVQGIIWGI
510 520 530 540
NSFDQWGVEL GKQLAKTILG ELTGETGPQK HDSSTERLIN LYLQTNRK
Length:548
Mass (Da):62,084
Last modified:October 1, 2000 - v1
Checksum:i28A85A19BFF174E1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE002098 Genomic DNA. Translation: AAF41752.1.
PIRiC81089.
RefSeqiNP_274402.1. NC_003112.2.

Genome annotation databases

EnsemblBacteriaiAAF41752; AAF41752; NMB1388.
GeneIDi903810.
KEGGinme:NMB1388.
PATRICi20358457. VBINeiMen85645_1740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE002098 Genomic DNA. Translation: AAF41752.1 .
PIRi C81089.
RefSeqi NP_274402.1. NC_003112.2.

3D structure databases

ProteinModelPortali Q9JYX3.
SMRi Q9JYX3. Positions 3-545.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 122586.NMB1388.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF41752 ; AAF41752 ; NMB1388 .
GeneIDi 903810.
KEGGi nme:NMB1388.
PATRICi 20358457. VBINeiMen85645_1740.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci NMEN122586:GHGG-1426-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC58.

Entry informationi

Entry nameiG6PI1_NEIMB
AccessioniPrimary (citable) accession number: Q9JYX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3