Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9JYM9 (PNCB_NEIMB) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:NMB1505
OrganismNeisseria meningitidis serogroup B (strain MC58) [Reference proteome] [HAMAP]
Taxonomic identifier122586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205834

Sequences

Sequence LengthMass (Da)Tools
Q9JYM9 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D6B618EEC5CC4A86

FASTA40246,310
        10         20         30         40         50         60 
MTGIIHSLLD TDLYKFTMLQ VVLHQFPQTH SLYEFRCRNA STVYPLADIR EDLEAELDAL 

        70         80         90        100        110        120 
CQLRFTHDEL GYLRSLRFIK SDFVDYLELF QLQRRFVEIG TDDKDRLNIR IEGPMIQAMF 

       130        140        150        160        170        180 
FEIFILAIVN ELYFRRLETP AVIEEGERRL QAKAARLKEI AAAQNPDEPP FLISDFGTRR 

       190        200        210        220        230        240 
RYKLAWQEHV IRTLLEAAPG IVRGTSNVFL AKKLGITPIG TMAHEFLQAF QALDVRLRNF 

       250        260        270        280        290        300 
QKAALESWVH EYRGDLGVAL TDVVGMDAFL RDFDLYFAKL FDGLRHDSGD PYVWGDKAYA 

       310        320        330        340        350        360 
HYQKLKIDSR TKMLTFSDGL DIERSWALHQ YFKDRFKTGF GIGTNLTNDM GHTPLNIVLK 

       370        380        390        400 
LVECNGQSVA KLSDSPGKTM TNNSTFLAYL RQVFDVPEPE TP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002098 Genomic DNA. Translation: AAF41861.1.
PIRE81075.
RefSeqNP_274513.1. NC_003112.2.

3D structure databases

ProteinModelPortalQ9JYM9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING122586.NMB1505.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF41861; AAF41861; NMB1505.
GeneID903949.
KEGGnme:NMB1505.
PATRIC20358792. VBINeiMen85645_1906.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMALYKFTMW.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycNMEN122586:GHGG-1545-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_NEIMB
AccessionPrimary (citable) accession number: Q9JYM9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways