ID   Q9JXT3_NEIMB            Unreviewed;       267 AA.
AC   Q9JXT3;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Type II restriction enzyme DpnI {ECO:0000313|EMBL:AAF42227.1};
DE            EC=3.1.21.4 {ECO:0000313|EMBL:AAF42227.1};
GN   Name=dpnC {ECO:0000313|EMBL:AAF42227.1};
GN   OrderedLocusNames=NMB1896 {ECO:0000313|EMBL:AAF42227.1};
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586 {ECO:0000313|EMBL:AAF42227.1, ECO:0000313|Proteomes:UP000000425};
RN   [1] {ECO:0000313|EMBL:AAF42227.1, ECO:0000313|Proteomes:UP000000425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58 {ECO:0000313|EMBL:AAF42227.1,
RC   ECO:0000313|Proteomes:UP000000425};
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R., Peterson J.D., Hickey E.K., Haft D.H., Salzberg S.L.,
RA   White O., Fleischmann R.D., Dougherty B.A., Mason T., Ciecko A.,
RA   Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H., Qin H., Vamathevan J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
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DR   EMBL; AE002098; AAF42227.1; -; Genomic_DNA.
DR   PIR; F81029; F81029.
DR   RefSeq; NP_274891.1; NC_003112.2.
DR   RefSeq; WP_002225800.1; NC_003112.2.
DR   AlphaFoldDB; Q9JXT3; -.
DR   STRING; 122586.NMB1896; -.
DR   REBASE; 111912; NmeMC58ORF1896P.
DR   PaxDb; 122586-NMB1896; -.
DR   KEGG; nme:NMB1896; -.
DR   PATRIC; fig|122586.8.peg.2419; -.
DR   HOGENOM; CLU_095681_0_0_4; -.
DR   InParanoid; Q9JXT3; -.
DR   OrthoDB; 1664032at2; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0009036; F:type II site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   CDD; cd22319; DpnI-like; 1.
DR   Gene3D; 3.40.210.30; Dam replacing family, catalytic PD-(D/E)XK domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR010324; DRP.
DR   InterPro; IPR041368; DRP_C.
DR   InterPro; IPR043025; DRP_PD-(D/E)XK_dom.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF06044; DpnI; 1.
DR   Pfam; PF17726; DpnI_C; 1.
DR   SUPFAM; SSF144020; FdhE-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AAF42227.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000425}.
FT   DOMAIN          184..252
FT                   /note="Dam-replacing protein HTH"
FT                   /evidence="ECO:0000259|Pfam:PF17726"
SQ   SEQUENCE   267 AA;  31293 MW;  D8B82C85A8CA8B09 CRC64;
     MNLFFDTELG KQQNKATHKI RVMSEAWLEK NGYCPCCGSK PMQRFANNKP VADLFCPNCH
     EQYELKSKNQ KTIGNSVPDG AYHTMLERIR SDTNPNFFFL AYKKADYSIR QLVLVPKHFI
     TPDMIIPRNK GIKNRPNHIM CSINLAPLPE SGKIFLIDNS RIIEPETVLK KWQSNLFLRN
     QNAERKGWLL AVMKCIDQLP EEFTLSQMYE FENKLSIQFP QNNHIRDKIR QQLQILRDQN
     TIEFIGRGLY KKSINCAQLP RYFDFKS
//