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Q9JXG5 (CAPP_NEIMB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:NMB2061
OrganismNeisseria meningitidis serogroup B (strain MC58) [Reference proteome] [HAMAP]
Taxonomic identifier122586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length900 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 900900Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166604

Sites

Active site1401 By similarity
Active site5681 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9JXG5 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 489B26F74AA06012

FASTA900101,210
        10         20         30         40         50         60 
MQLHILNNPK DAALAADAEF LKQSLFNLLH EEASPLVVET VKLLSTSDDS AALIEKVLPQ 

        70         80         90        100        110        120 
LDEQQTHDLT LACGLFAQIL NIAEDVHHER RRQIHEEAGR GGAEGSLTET VRRLKAGKAD 

       130        140        150        160        170        180 
GKSVQRQLDN TSVTAVLTAH PTEVQRQTVL SFNRRIRALL PQRERCTNAD ALARLRREID 

       190        200        210        220        230        240 
TILLGLWQTS ETRRHKLSVN DEINNGVSIF PMSFFEALPK LYRKMEHDFQ TAYPGVRVPD 

       250        260        270        280        290        300 
ILKIGGWIGG DRDGNPFVSA ETLRFAFRRH ADAVFRFYRG ELDKLYRELP LSIRRVKVNG 

       310        320        330        340        350        360 
DVTALSDKSP DEEIARAEEP YRRAIAYIMA RAMGKARALG LGMGCKFGFL EPYASAQEFL 

       370        380        390        400        410        420 
DDLKKLQRSL IDNGSRLLAE GRLADLIRSV SVFGFHMMPL DLRQHAGKHA DVVAELFQHA 

       430        440        450        460        470        480 
GLEDYNRLNE EQKQTALLRE LSHQRPLYSP FITYSDHTRH ELAIFNEARK IKDEFGEDAV 

       490        500        510        520        530        540 
TQSIISNCEQ PSDLLALALL LKETGLLAVE NGKPHSRINI VPLFETIEAL ENACPVMETM 

       550        560        570        580        590        600 
FRLDWYDALL ESRGNIQEIM LGYSDSNKDG GYVTSSWCLY QAELGLVELF KKYDVRMRLF 

       610        620        630        640        650        660 
HGRGGSVGRG GGPSYQAILA QPAGSVAGQI RITEQGEVIT AKYADPGNAQ RNLETLVAAT 

       670        680        690        700        710        720 
LEASILPDKK DPDAKLMQAL SDVSFKYYRE LITHPDFIDY FLQTSPIQEI ATLNLGSRPA 

       730        740        750        760        770        780 
SRKTLARIQD LRAIPWVFSW MQNRLMLPAW YGFGSAVETL CEDKPETLAA LREHAQSNPF 

       790        800        810        820        830        840 
FQAMLSNMEQ VMAKTDITLA ENYAGLSESP DKAKIIFGMI KEEYRRSRKA LLDLLQTEEL 

       850        860        870        880        890        900 
LRDNRSLARS LALRIPYLNA LNGLQVAMLK RLRKEPDNPH ALLMVHLTIN GVAQGLRNTG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002098 Genomic DNA. Translation: AAF42380.1.
PIRA81010.
RefSeqNP_275051.1. NC_003112.2.

3D structure databases

ProteinModelPortalQ9JXG5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING122586.NMB2061.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF42380; AAF42380; NMB2061.
GeneID904019.
KEGGnme:NMB2061.
PATRIC20360278. VBINeiMen85645_2639.

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAELSTISC.
OrthoDBEOG6TJ7T8.

Enzyme and pathway databases

BioCycNMEN122586:GHGG-2124-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_NEIMB
AccessionPrimary (citable) accession number: Q9JXG5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families